SCHEMBL18302008

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16219714	0.89	SLC6A3 (0.50)	SLC6A3SLC6A4SLC6A2ABCG2ALDH1A1
	SCHEMBL21102265	0.88	SLC6A3 (0.49)	SLC6A3SLC6A4SLC6A2ABCG2ALDH1A1
	SCHEMBL18553364	0.86	SLC6A3 (0.57)	SLC6A3SLC6A4SLC6A2ABCG2ALDH1A1
	SCHEMBL17836985	0.85	CDC25B (0.54)	ALDH1A1KDM4EL3MBTL1MAPTMEN1
	SCHEMBL10010690	0.84	SLC6A3 (0.58)	SLC6A3SLC6A4SLC6A2ALDH1A1KDM4E
	SCHEMBL6775688	0.83	SLC6A3 (0.49)	SLC6A3SLC6A4SLC6A2ALDH1A1KDM4E
	SCHEMBL16321648	0.83	SLC6A3 (0.47)	SLC6A3SLC6A4SLC6A2ABCG2ALDH1A1
	SCHEMBL20068680	0.80	SLC6A3 (0.40)	SLC6A3SLC6A4SLC6A2ABCG2ALDH1A1
	SCHEMBL6776215	0.80	SLC6A2 (0.46)	SLC6A3SLC6A4SLC6A2ALDH1A1KDM4E
	Bicarbonate SCHEMBL27467972	0.80	SLC6A3 (0.54)	SLC6A3SLC6A4SLC6A2ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.