Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 6/20 | 0.33 |
| ▸ | IDH2 | P48735 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20561582 | 1.00 | MEN1 (0.34) | MEN1CYP1A2KMT2ATSHRHTR3E | |
| SCHEMBL18304578 | 1.00 | MEN1 (0.34) | MEN1CYP1A2KMT2ATSHRHTR3E | |
| SCHEMBL30233615 | 0.80 | — | — | |
| SCHEMBL24575808 | 0.79 | HTR1A (0.40) | — | |
| SCHEMBL161142 | 0.72 | ALDH1A1 (0.40) | MEN1CYP1A2KMT2ANPSR1 | |
| SCHEMBL9302323 | 0.72 | NPC1 (0.41) | MEN1CYP1A2KMT2ACYP2D6ALOX15 | |
| SCHEMBL9711369 | 0.71 | PPARA (0.31) | — | |
| SCHEMBL17449293 | 0.71 | IDH1 (0.41) | MEN1CYP1A2KMT2ATSHRHTR3E | |
| SCHEMBL17449295 | 0.70 | MEN1 (0.42) | MEN1CYP1A2KMT2ATSHRHTR3E | |
| SCHEMBL31108761 | 0.70 | MEN1 (0.42) | MEN1CYP1A2KMT2ATSHRHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10464861-B2 | Asymmetric addition reactions | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2019-11-05 | — | — | US | disclosed |
| EP-3307698-B1 | ASYMMETRIC ADDITION REACTIONS | UNIV OXFORD INNOVATION LTD (GB) | 2019-09-18 | — | — | EP | disclosed |
| EP-3307698-B1 | ASYMMETRIC ADDITION REACTIONS | UNIV OXFORD INNOVATION LTD (GB) | 2019-09-18 | — | — | EP | disclosed |
| US-20180334414-A1 | ASYMMETRIC ADDITION REACTIONS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2018-11-22 | — | — | US | disclosed |
| EP-3307698-A1 | ASYMMETRIC ADDITION REACTIONS | Oxford University Innovation Limited (GB) | 2018-04-18 | — | — | EP | disclosed |
| WO-2016198836-A1 | ASYMMETRIC ADDITION REACTIONS | ISIS INNOVATION LIMITED (GB) | 2016-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10464861-B2 | Asymmetric addition reactions | CSPP1, CCRL2, CBR3 | MEN1 4406/4885CYP1A2 72/4885KMT2A 3951/4885 |
| US-20180334414-A1 | ASYMMETRIC ADDITION REACTIONS | CSPP1, CCRL2, CBR3 | MEN1 4406/4885CYP1A2 72/4885KMT2A 3951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.