SCHEMBL18306136

SCHEMBL18306136

O=[N+]([O-])c1cc(O)cc(O)c1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 4/20 0.67
GPR35 Q9HC97 2/20 0.67
MEN1 O00255 2/20 0.67
ALDH1A1 P00352 2/20 0.67
MAPT P10636 2/20 0.67
HPGD P15428 2/20 0.67
RECQL P46063 2/20 0.67
KMT2A Q03164 2/20 0.67
KDM4E B2RXH2 1/20 0.67
CYP1A2 P05177 1/20 0.67
CYP2C9 P11712 1/20 0.67
ALOX15 P16050 1/20 0.67
ALOX12 P18054 1/20 0.67
MAPK1 P28482 1/20 0.67
PMP22 Q01453 1/20 0.67
HIF1A Q16665 1/20 0.67
HSD17B10 Q99714 1/20 0.67
TDP1 Q9NUW8 1/20 0.67
XDH P47989 1/20 0.60
CA12 O43570 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70447 0.88 GPR35 (0.67) TTRGPR35MEN1ALDH1A1MAPT
SCHEMBL14155059 0.80 ALOX15 (0.64) TTRGPR35MEN1ALDH1A1MAPT
SCHEMBL13834396 0.80 GPR35 (0.53) TTRGPR35MEN1ALDH1A1MAPT
3,5-Dinitrocatechol (Or-486) SCHEMBL1283419 0.80 GPR35 (1.00) TTRGPR35MEN1ALDH1A1MAPT
Methoxymethane SCHEMBL9777340 0.80 GPR35 (0.63) TTRGPR35MEN1ALDH1A1MAPT
SCHEMBL15769323 0.78 GPR35 (0.62) TTRGPR35MEN1ALDH1A1MAPT
SCHEMBL4847900 0.78 GPR35 (0.80) TTRGPR35MEN1ALDH1A1MAPT
SCHEMBL4167284 0.78 ERN1 (0.62) TTRGPR35MEN1ALDH1A1MAPT
SCHEMBL3858194 0.78 TTR (0.67) TTRGPR35MEN1ALDH1A1MAPT
SCHEMBL4172077 0.78 TTR (0.67) TTRGPR35MEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109616629-B Lithium-supplementing positive electrode active material, positive electrode material, lithium ion battery, and preparation and application of lithium-supplementing positive electrode active material 中南大学 2020-05-22 CN disclosed
CN-109616629-A A kind of benefit lithium positive electrode active materials, positive electrode, lithium ion battery and its preparation and application 中南大学 2019-04-12 CN disclosed
WO-2016199943-A1 HETEROCYCLIC COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-12-15 WO disclosed
WO-2016199943-A1 HETEROCYCLIC COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-12-15 WO disclosed