SCHEMBL183063

SCHEMBL183063

S=C(S)c1cccc2c1Cc1ccccc1N2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
NPC1 O15118 2/20 0.44
HSP90AA1 P07900 1/20 0.44
THRB P10828 1/20 0.44
HK1 P19367 1/20 0.44
MAPK1 P28482 1/20 0.44
RECQL P46063 1/20 0.44
RAB9A P51151 1/20 0.44
GALK1 P51570 1/20 0.44
BLM P54132 1/20 0.44
HKDC1 Q2TB90 1/20 0.44
AHR P35869 1/20 0.41
PDK2 Q15119 1/20 0.41
SRC P12931 2/20 0.40
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL496850 0.79 TRPA1 (0.49) MAPTKDM4EMEN1KMT2ANPC1
SCHEMBL28278484 0.77 TRPA1 (0.50) MAPTKDM4EMEN1KMT2ANPC1
SCHEMBL15196679 0.74 MAPT (0.56) MAPTKDM4EMEN1KMT2ANPC1
SCHEMBL7516634 0.74 MEN1 (0.47) MAPTKDM4EMEN1KMT2ANPC1
SCHEMBL7200083 0.74 AHR (0.41) MAPTKDM4EMEN1KMT2ANPC1
SCHEMBL29757969 0.73 NPC1 (0.50) MAPTKDM4EMEN1KMT2ANPC1
SCHEMBL25275193 0.70 MAPT (0.47) MAPTKDM4EMEN1KMT2ANPC1
SCHEMBL88280 0.70 MAPT (0.47) MAPTKDM4EMEN1KMT2ANPC1
SCHEMBL5141694 0.70 NPC1 (0.47) MAPTKDM4EMEN1KMT2ANPC1
SCHEMBL29896031 0.70 MAPT (0.47) MAPTKDM4EMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12379379-B2 Assay NEOGEN FOOD SAFETY US HOLDCO CORPORATION (US) 2025-08-05 US disclosed
US-RE49466-E1 Solution phase homogeneous assays BECKMAN COULTER, INC. (US) 2023-03-21 US disclosed
EP-3821249-B1 SPECIFIC BINDING CHEMILUMINESCENT ASSAY 3M INNOVATIVE PROPERTIES CO (US) 2022-06-29 EP disclosed
US-11320424-B2 Specific binding chemiluminescent assay 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-05-03 US disclosed
US-20210293795-A1 SPECIFIC BINDING CHEMILUMINESCENT ASSAY JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2021-09-23 US disclosed
EP-3821249-A1 SPECIFIC BINDING CHEMILUMINESCENT ASSAY 3M Innovative Properties Company (US) 2021-05-19 EP disclosed
EP-3821029-A1 ASSAY 3M Innovative Properties Company (US) 2021-05-19 EP disclosed
WO-2020012390-A1 SPECIFIC BINDING CHEMILUMINESCENT ASSAY 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-01-16 WO disclosed
WO-2020012391-A1 ASSAY 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-01-16 WO disclosed
US-10036708-B2 Solution phase homogeneous assays BECKMAN COULTER, INC. (US) 2018-07-31 US disclosed
EP-2401392-B1 SOLUTION PHASE HOMOGENEOUS ASSAYS BECKMAN COULTER INC (US) 2017-01-25 EP disclosed
US-20150212005-A1 SOLUTION PHASE HOMOGENEOUS ASSAYS BECKMAN COULTER, INC. 2015-07-30 US disclosed
US-9029092-B2 Solution phase homogeneous assays BECKMAN COULTER, INC. (US) 2015-05-12 US disclosed
EP-2401393-A1 NON SEPARATION ASSAYS WITH SELECTIVE SIGNAL INHIBITORS Beckman Coulter, Inc. (US) 2012-01-04 EP disclosed
EP-2401392-A1 SOLUTION PHASE HOMOGENEOUS ASSAYS Beckman Coulter, Inc. (US) 2012-01-04 EP disclosed
US-20100273189-A1 NON SEPARATION ASSAYS WITH SELECTIVE SIGNAL INHIBITORS BECKMAN COULTER, INC. (US) 2010-10-28 US disclosed
US-20100267071-A1 SOLUTION PHASE HOMOGENEOUS ASSAYS BECKMAN COULTER, INC. (US) 2010-10-21 US disclosed
WO-2010099479-A1 NON SEPARATION ASSAYS WITH SELECTIVE SIGNAL INHIBITORS BECKMAN COULTER, INC. (US) 2010-09-02 WO disclosed
WO-2010099486-A1 SOLUTION PHASE HOMOGENEOUS ASSAYS BECKMAN COULTER, INC. (US) 2010-09-02 WO disclosed