SCHEMBL88280

SCHEMBL88280

Nc1cccc2c1Cc1ccccc1N2

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.47
KDM4E B2RXH2 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
NPC1 O15118 2/20 0.47
AHR P35869 1/20 0.47
PDK2 Q15119 1/20 0.47
HSP90AA1 P07900 1/20 0.47
THRB P10828 1/20 0.47
HK1 P19367 1/20 0.47
MAPK1 P28482 1/20 0.47
RECQL P46063 1/20 0.47
RAB9A P51151 1/20 0.47
GALK1 P51570 1/20 0.47
BLM P54132 1/20 0.47
HKDC1 Q2TB90 1/20 0.47
SRC P12931 2/20 0.45
GAA P10253 2/20 0.44
HTR5A P47898 5/20 0.43
CD44 P16070 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29896031 1.00 MAPT (0.47) MAPTKDM4EMEN1KMT2ANPC1
SCHEMBL15196679 0.81 MAPT (0.56) MAPTKDM4EMEN1KMT2ANPC1
SCHEMBL29757969 0.80 NPC1 (0.50) MAPTKDM4EMEN1KMT2ANPC1
SCHEMBL9725644 0.80 PARP1 (0.47) MAPTKDM4EMEN1KMT2ANPC1
SCHEMBL9852644 0.80 CASP7 (0.53) MAPTMEN1KMT2AAHRPDK2
SCHEMBL25275193 0.77 MAPT (0.47) MAPTKDM4EMEN1KMT2ANPC1
SCHEMBL5141694 0.77 NPC1 (0.47) MAPTKDM4EMEN1KMT2ANPC1
SCHEMBL7516634 0.77 MEN1 (0.47) MAPTKDM4EMEN1KMT2ANPC1
Acridan SCHEMBL20594012 0.76 MAPT (0.65) MAPTKDM4EMEN1KMT2ANPC1
Acridan SCHEMBL183367 0.76 MAPT (0.65) MAPTKDM4EMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 437 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8506695-B2 Matrix of oligomer of tripropylene glycol diacrylate, melamine acrylate, amine functional polyester acrylate, hexanediol diacrylate, dendritic polyester-based acrylate, and/or bisphenol-A epoxy diacrylate with activator dissolved ; 4,4*-dihydroxydiphenyl sulfone color former; leuco dye; packages HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2013-08-13 US claimed
US-7575844-B2 Color forming composites capable of multi-colored imaging and associated systems and methods HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2009-08-18 US claimed
US-7501172-B2 Integrated recording and labeling with optical recording device HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2009-03-10 US claimed
EP-1264212-B1 ELEMENTS FOR FORMING PRINT-OUT IMAGES DU PONT (US) 2009-02-18 EP claimed
US-7462443-B2 Leuco dye-containing coating compositions HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2008-12-09 US claimed
US-20080268384-A1 Color forming composites capable of multi-colored imaging and associated systems and methods HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2008-10-30 US claimed
US-20080214392-A1 INKS FOR USE ON LIGHT-ACTIVATED IMAGING MEDIA GORE MAKARAND P 2008-09-04 US claimed
US-20080103042-A1 Matrix of oligomer of tripropylene glycol diacrylate, melamine acrylate, amine functional polyester acrylate, hexanediol diacrylate, dendritic polyester-based acrylate, and/or bisphenol-A epoxy diacrylate with activator dissolved ; 4,4*-dihydroxydiphenyl sulfone color former; leuco dye; packages HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2008-05-01 US claimed
US-7329630-B2 Stabilizers and anti-fade agents for use in infrared sensitive leuco dye compositions HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2008-02-12 US claimed
US-7270932-B2 Imaging composition and method ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2007-09-18 US claimed
US-20020146649-A1 Elements for forming print-out images E. I. DU PONT DE NEMOURS AND COMPANY 2002-10-10 US claimed
WO-2001067175-A2 ELEMENTS FOR FORMING PRINT-OUT IMAGES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2001-09-13 WO claimed
US-6251571-B1 MIXTURE OF OXIDIZER, DYE AND HYDROXYLAMINE E. I. DU PONT DE NEMOURS AND COMPANY 2001-06-26 US claimed
EP-0941866-A1 Non-photosensitive, thermally imageable element having improved room light stability E. I. du Pont de Nemours and Company (US) 1999-09-15 EP claimed
US-5744280-A MONOCHROME IMAGES;IMPROVED CONTRAST E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-04-28 US claimed
EP-0828182-A1 Storage-stable photoimageable compositions with improved leuco dye E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-03-11 EP claimed
US-5055373-A Support with coating layer of microcapsules containing leuco dyes and photooxidizer and external reducing agent FUJI PHOTO FILM CO., LTD. (JP) 1991-10-08 US claimed
US-4929530-A OXIDATIVE LEUCO DYES, PHOTO-OXIDIZERS, REDUCING AGENTS, ORGANIC SULFONAMIDES AND PHENOLIC COMPONENTS; EXPOSING TO LIGHT FUJI PHOTO FILM CO., LTD. (JP) 1990-05-29 US claimed
US-4634657-A AND A LEEVCO DYE, MONOMERIC COMPOUND AND PHOTOINIATOR; IMPROVED PRINTOUT CAPABILITIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-01-06 US claimed
US-4090877-A COLOR PHOTOGRAPHY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-05-23 US claimed