Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HK1 | P19367 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GALK1 | P51570 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200083 | 0.81 | AHR (0.41) | AHRPDK2SRCHSP90AA1ALDH1A1 | |
| SCHEMBL14444038 | 0.80 | ALOX5 (0.54) | TRPA1AHRPDK2SRCHSP90AA1 | |
| SCHEMBL4407214 | 0.79 | CRBN (0.50) | AHRPDK2ALOX5MEN1KMT2A | |
| SCHEMBL21027973 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KMT2ANPC1MAPK1RAB9A | |
| SCHEMBL183063 | 0.79 | MAPT (0.44) | TRPA1AHRPDK2SRCHSP90AA1 | |
| SCHEMBL4915504 | 0.78 | TRPA1 (0.56) | TRPA1HSP90AA1ALDH1A1ALOX15KDM4E | |
| SCHEMBL6902823 | 0.77 | TRPA1 (0.55) | TRPA1HSP90AA1ALDH1A1ALOX15KDM4E | |
| SCHEMBL15196679 | 0.76 | MAPT (0.56) | AHRPDK2SRCHSP90AA1ALOX15 | |
| Acridan SCHEMBL4012624 | 0.75 | MAPT (0.60) | AHRPDK2SRCHSP90AA1ALDH1A1 | |
| SCHEMBL7516634 | 0.75 | MEN1 (0.47) | AHRPDK2SRCHSP90AA1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1353908-B1 | PROCESSES AND SYNTHETIC INTERMEDIATES FOR PREPARING N-ARYLACRIDANCARBOXYLIC ACID DERIVATIVES | LUMIGEN INC (US) | 2006-03-08 | — | — | EP | claimed |
| EP-1353908-A4 | PROCESSES AND SYNTHETIC INTERMEDIATES FOR PREPARING N-ARYLACRIDANCARBOXYLIC ACID DERIVATIVES | LUMIGEN INC (US) | 2004-01-28 | — | — | EP | claimed |
| EP-1353908-A1 | PROCESSES AND SYNTHETIC INTERMEDIATES FOR PREPARING N-ARYLACRIDANCARBOXYLIC ACID DERIVATIVES | LUMIGEN, INC. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002059096-A1 | PROCESSES AND SYNTHETIC INTERMEDIATES FOR PREPARING N-ARYLACRIDANCARBOXYLIC ACID DERIVATIVES | LUMIGEN, INC. (US) | 2002-08-01 | — | — | WO | claimed |
| US-6410732-B2 | FORMATION OF BOND BETWEEN NITROGEN ATOM OF ACRIDAN RING AND CARBON ATOM OF ANOTHER AROMATIC OR HETEROAROMATIC RING COMPOUND; ASSAYS FOR PEROXIDASE ENZYMES AND ENZYME INHIBITORS AND IN ASSAYS EMPLOYING ENZYME-LABELED SPECIFIC BINDING PAIRS | LUMIGEN, INC. | 2002-06-25 | — | — | US | claimed |
| US-20010031869-A1 | Processes and synthetic intermediates for preparing N-arylacridancarboxylic acid derivatives | LUMIGEN, INC. | 2001-10-18 | — | — | US | claimed |
| US-11345692-B1 | 3-vinylquinolines as cancer cells inhibitors | KING ABDULAZIZ UNIVERSITY (SA) | 2022-05-31 | — | — | US | disclosed |
| US-10882852-B1 | 3-vinylquinolines as cancer cells inhibitors | KING ABDULAZIZ UNIVERSITY (SA) | 2021-01-05 | — | — | US | disclosed |
| EP-1509601-B1 | FLUORESCENT DETECTION OF PEROXIDASE ENZYMES | LUMIGEN INC (US) | 2012-12-05 | — | — | EP | disclosed |
| US-8106203-B2 | Assay methods using chemiluminescent detection of peroxidase | LUMIGEN, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| EP-2096110-B1 | Acridane-9-dithiocarboxylate derivatives for generating chemiluminescence with a peroxidase | LUMIGEN INC (US) | 2011-06-22 | — | — | EP | disclosed |
| US-20100086929-A1 | DETECTION OF ANALYTES | DO-COOP TECHNOLOGIES LTD. (IL) | 2010-04-08 | — | — | US | disclosed |
| EP-2122350-A2 | DETECTION OF ANALYTES | Do-Coop Technologies Ltd (IL) | 2009-11-25 | — | — | EP | disclosed |
| EP-0755457-A4 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN INC (US) | 1997-07-16 | — | — | EP | disclosed |
| EP-0778946-A1 | NOVEL METHOD AND KITS FOR PRODUCING LIGHT FROM AN ACRIDAN COMPOUND | LUMIGEN, INC. (US) | 1997-06-18 | — | — | EP | disclosed |
| EP-0755457-A1 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN, INC. (US) | 1997-01-29 | — | — | EP | disclosed |
| US-5523212-A | OXIDATION WITH PEROXIDE AND PEROXIDASE TO EXCITED ACRIDONE DERIVATIVE; DETECTING PROTEINS, HAPTENS, ANTIBODIES, ENZYMES | LUMIGEN, INC. (US) | 1996-06-04 | — | — | US | disclosed |
| WO-1996007912-A1 | NOVEL METHOD AND KITS FOR PRODUCING LIGHT FROM AN ACRIDAN COMPOUND | LUMIGEN, INC. (US) | 1996-03-14 | — | — | WO | disclosed |
| WO-1995028495-A1 | NOVEL ARYL-N-ALKYLACRIDANTHIOCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN, INC. (US) | 1995-10-26 | — | — | WO | disclosed |
| WO-1994026927-A1 | NOVEL N-ALKYLACRIDAN CARBOXYL DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN, INC. (US) | 1994-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10882852-B1 | 3-vinylquinolines as cancer cells inhibitors | MCL1, VHL, API5 | TRPA1 4825/4885AHR 3280/4885PDK2 729/4885 |
| US-11345692-B1 | 3-vinylquinolines as cancer cells inhibitors | MCL1, VHL, API5 | TRPA1 4825/4885AHR 3280/4885PDK2 729/4885 |
| US-20010031869-A1 | Processes and synthetic intermediates for preparing N-arylacridancarboxylic acid derivatives | ALDH3A1, AADAC, SPR | TRPA1 4237/4885AHR 254/4885PDK2 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.