Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 10/20 | 0.56 |
| ▸ | MGAM | O43451 | 9/20 | 0.56 |
| ▸ | SI | P14410 | 9/20 | 0.56 |
| ▸ | MGAM2 | Q2M2H8 | 9/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 3/20 | 0.53 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18311339 | 0.91 | GAA (0.56) | ESR1ESR2GAAMGAMSI | |
| SCHEMBL18308825 | 0.91 | ESR1 (0.62) | ESR1ESR2GAAMGAMSI | |
| SCHEMBL18311338 | 0.87 | GAA (0.48) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL19091249 | 0.81 | GAA (0.52) | ESR1ESR2GAAMGAMSI | |
| SCHEMBL9446140 | 0.81 | ESR2 (0.73) | ESR1ESR2GAAMGAMSI | |
| SCHEMBL18411605 | 0.80 | GAA (0.65) | ESR1ESR2GAAMGAMSI | |
| SCHEMBL30504167 | 0.79 | NR5A1 (0.57) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL20928730 | 0.79 | NR5A1 (0.57) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL3810477 | 0.79 | ESR2 (0.71) | ESR1ESR2GAAMGAMSI | |
| SCHEMBL14354863 | 0.78 | CYP2D6 (0.51) | GAAMEN1NPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160362606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160362606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, PLEC, EML4 | ESR1 3527/4885ESR2 4381/4885GAA 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.