Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | MGAM | O43451 | 4/20 | 0.48 |
| ▸ | SI | P14410 | 4/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.45 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.45 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.45 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.45 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.45 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17485686 | 0.91 | PTPN11 (0.49) | GAAPTPN11CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL18311339 | 0.90 | GAA (0.56) | GAAMGAMSIMGAM2PTPN11 | |
| SCHEMBL18311341 | 0.87 | ESR1 (0.59) | GAAMGAMSIMGAM2CYP3A4 | |
| SCHEMBL14354863 | 0.85 | CYP2D6 (0.51) | GAAPTPN11CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL18308824 | 0.83 | ALDH1A1 (0.44) | GAAMGAMSIMGAM2CYP3A4 | |
| SCHEMBL18308825 | 0.83 | ESR1 (0.62) | GAAMGAMSIMGAM2 | |
| SCHEMBL18411547 | 0.82 | GAA (0.56) | GAAMGAMSIMGAM2CYP4F2 | |
| SCHEMBL25852886 | 0.80 | PTPN11 (0.54) | PTPN11CYP3A4CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL18682514 | 0.80 | CYP3A4 (0.66) | CYP3A4CYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15162229 | 0.80 | NR1I2 (0.64) | GAACYP3A4CYP2D6CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3121247-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | Merck Patent GmbH (DE) | 2017-01-25 | — | — | EP | disclosed |
| US-20160362606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160362606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, PLEC, EML4 | GAA 3645/4885MGAM 541/4885SI 3143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.