Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9436923 | 0.82 | NPC1 (0.57) | CYP3A4TDP1ALOX15TP53THRB | |
| SCHEMBL11855115 | 0.78 | NPC1 (0.42) | CYP3A4TDP1ALOX15TP53THRB | |
| SCHEMBL22006154 | 0.77 | CYP3A4 (0.52) | CYP3A4TDP1ALOX15TP53THRB | |
| SCHEMBL12181231 | 0.77 | CYP3A4 (0.52) | CYP3A4TDP1ALOX15TP53THRB | |
| SCHEMBL13405565 | 0.76 | CYP3A4 (0.48) | CYP3A4TDP1ALOX15TP53THRB | |
| SCHEMBL12589735 | 0.76 | RAB9A (0.50) | CYP3A4TDP1ALOX15TP53THRB | |
| SCHEMBL11667712 | 0.76 | CYP3A4 (0.50) | CYP3A4TDP1ALOX15TP53THRB | |
| SCHEMBL14159459 | 0.76 | CYP3A4 (0.56) | CYP3A4TDP1ALOX15TP53THRB | |
| SCHEMBL15919036 | 0.74 | ALDH1A1 (0.48) | CYP3A4TDP1ALOX15TP53THRB | |
| SCHEMBL10189290 | 0.74 | GAA (0.40) | CYP3A4TDP1ALOX15TP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058501-A1 | OXIDIZED GLUTATHIONE ASSAY | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2012-03-08 | — | — | US | disclosed |