Acetamide

Acetamide

SCHEMBL18319481

C=CCN(C)C.CC(N)=O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
ALOX15 P16050 1/20 0.40
BLM P54132 1/20 0.40
PMP22 Q01453 1/20 0.40
ALDH1A1 P00352 3/20 0.38
TSHR P16473 1/20 0.35
FGFR4 P22455 1/20 0.35
TDP1 Q9NUW8 1/20 0.33
DPP4 P27487 1/20 0.33
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12096341 0.89 TDP1 (0.52) ALDH1A1TSHRFGFR4TDP1DPP4
Acrylamide SCHEMBL29019443 0.88 ALDH1A1 (0.52) LMNAALDH1A1TSHRFGFR4DPP4
Acetic Acid SCHEMBL1077081 0.87 ALDH1A1 (0.39) LMNAALDH1A1TSHRMEN1KMT2A
Acrylamide SCHEMBL27520394 0.86 ALDH1A1 (0.50) LMNAALDH1A1TSHRFGFR4DPP4
Acrylamide SCHEMBL8165211 0.86 ALDH1A1 (0.50) LMNAALDH1A1TSHRFGFR4DPP4
Butanedione SCHEMBL27468486 0.85 ALDH1A1 (0.38) LMNAALDH1A1TSHRMEN1KMT2A
Bicarbonate SCHEMBL28060031 0.84 ALDH1A1 (0.41) LMNAALOX15ALDH1A1TSHRDPP4
Bicarbonate SCHEMBL28060029 0.84 ALDH1A1 (0.41) LMNAALOX15ALDH1A1TSHRDPP4
Hydroxyamine SCHEMBL27886493 0.84
Glycine SCHEMBL29866 0.81 GLRA1 (0.46) LMNAALOX15BLMALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160367705-A1 NANOPARTICLES COMPRISED OF SHELLS ASSOCIATED WITH CHARGED ENTITIES AND FORMED FROM MONOMERS AND METHODS OF MAKING AND USING NANOPARTICLES NEW YORK UNIVERSITY (US) 2016-12-22 US claimed
US-20240051832-A1 METHODS AND SYSTEMS FOR PRODUCING SOLID INORGANIC CARBONATE AND BICARBONATE COMPOUNDS CORNELL UNIVERSITY (US) 2024-02-15 US disclosed
EP-4208281-A2 METHODS AND SYSTEMS FOR PRODUCING SOLID INORGANIC CARBONATE AND BICARBONATE COMPOUNDS Cornell University (US) 2023-07-12 EP disclosed
US-20160367705-A1 NANOPARTICLES COMPRISED OF SHELLS ASSOCIATED WITH CHARGED ENTITIES AND FORMED FROM MONOMERS AND METHODS OF MAKING AND USING NANOPARTICLES NEW YORK UNIVERSITY (US) 2016-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160367705-A1 NANOPARTICLES COMPRISED OF SHELLS ASSOCIATED WITH CHARGED ENTITIES AND FORMED FROM MONOMERS AND METHODS OF MAKING AND USING NANOPARTICLES CHMP4B, RCC1, CD14 LMNA 145/4885ALOX15 3684/4885BLM 3386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.