Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.39 |
| ▸ | MYLK | Q15746 | 2/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519002 | 0.83 | PDE4A (0.42) | ALOX5PTGS2MAPTALDH1A1MEN1 | |
| SCHEMBL9518499 | 0.79 | CA1 (0.42) | MAPTALDH1A1KDM4EHTTGAA | |
| SCHEMBL1832013 | 0.77 | ERN1 (0.46) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL31432590 | 0.74 | HIF1A (0.53) | ALOX5PTGS2MAPTALDH1A1MEN1 | |
| SCHEMBL30958543 | 0.73 | PRKCE (0.41) | IDO1ALOX5MAPTALDH1A1MEN1 | |
| SCHEMBL11201117 | 0.71 | MEN1 (0.39) | IDO1ALOX5MAPTALDH1A1MEN1 | |
| SCHEMBL13318421 | 0.71 | MAOB (0.57) | MAPTALDH1A1MEN1RECQLKMT2A | |
| SCHEMBL16625523 | 0.71 | MAOB (0.52) | IDO1MAPTALDH1A1MEN1RECQL | |
| SCHEMBL25937354 | 0.71 | ERN1 (0.42) | ALOX5PTGS2MAPTALDH1A1KMT2A | |
| SCHEMBL29392084 | 0.71 | MAOB (0.52) | IDO1MAPTALDH1A1MEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269599-B1 | Substituted 1H-imidazoles | UCB SA (BE) | 1993-12-15 | — | — | EP | disclosed |
| US-4814343-A | ANTIISCHEMIC | U C B, S.A. (BE) | 1989-03-21 | — | — | US | disclosed |
| EP-0269599-A2 | Substituted 1H-imidazoles | U C B, S.A. (BE) | 1988-06-01 | — | — | EP | disclosed |