Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26088674 | 0.81 | USP2 (0.65) | USP2SMN1; SMN2ALOX15LMNAPKM | |
| SCHEMBL8123253 | 0.79 | USP2 (0.67) | USP2SMN1; SMN2ALOX15LMNAPKM | |
| SCHEMBL26104648 | 0.71 | PDE9A (0.47) | USP2SMN1; SMN2ALOX15LMNAPKM | |
| SCHEMBL8689140 | 0.71 | LMNA (0.46) | USP2SMN1; SMN2ALOX15LMNAPKM | |
| SCHEMBL31297127 | 0.70 | MAPT (0.40) | USP2SMN1; SMN2ALOX15LMNAPKM | |
| SCHEMBL3408224 | 0.66 | MAPT (0.50) | USP2SMN1; SMN2ALOX15LMNAKDM4E | |
| SCHEMBL8124714 | 0.65 | USP2 (1.00) | USP2SMN1; SMN2ALOX15LMNAPKM | |
| SCHEMBL1258695 | 0.64 | PTPN1 (0.42) | USP2LMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8113838 | 0.64 | USP2 (0.97) | USP2SMN1; SMN2ALOX15LMNAPKM | |
| SCHEMBL3527851 | 0.62 | GABRA1 (0.60) | SMN1; SMN2ALOX15LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016202898-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-22 | — | — | WO | disclosed |