SCHEMBL18320615

SCHEMBL18320615

Fc1cccnc1-c1nc(F)c(F)c(F)c1F

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRG2 P18507 7/20 0.37
GABRB3 P28472 7/20 0.37
GABRA5 P31644 7/20 0.37
GABRA3 P34903 7/20 0.37
GABRA1 P14867 6/20 0.37
CBFB Q13951 1/20 0.34
NPC1 O15118 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NAPRT Q6XQN6 1/20 0.32
TDP2 O95551 1/20 0.32
NSD2 O96028 1/20 0.32
ABL1 P00519 1/20 0.32
PLCG1 P19174 1/20 0.32
CES1 P23141 1/20 0.32
PAX8 Q06710 1/20 0.32
RIN1 Q13671 1/20 0.32
MEN1 O00255 1/20 0.32
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15624391 0.81 TDP1 (0.44) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL445036 0.73 MEN1 (0.31) MEN1KMT2A
SCHEMBL15624431 0.71
SCHEMBL30912195 0.69 CDC25B (0.38) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL29470040 0.69 GABRG2 (0.45) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL30912201 0.68 TRIM24 (0.39) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL16390264 0.68 CASP6 (0.37) GABRG2GABRB3GABRA5GABRA3CBFB
SCHEMBL19072767 0.68 GABRG2 (0.42) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL2639667 0.67 FEN1 (0.43) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL6979135 0.67 XDH (0.50) KDM4EMEN1KMT2ATDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10862153-B2 High-power redox flow battery based on the CrIII/CrVI redox couple and its mediated regeneration CHROME PLATED POWER LLC (US) 2020-12-08 US disclosed
EP-3311438-B1 HIGH-POWER REDOX FLOW BATTERY BASED ON THE CRIII/CRVI REDOX COUPLE AND ITS MEDIATED REGENERATION Chrome Plated Power SAS (FR) 2019-10-02 EP disclosed
US-20180366758-A1 HIGH-POWER REDOX FLOW BATTERY BASED ON THE CRIII/CRVI REDOX COUPLE AND ITS MEDIATED REGENERATION Chrome Plated Power SAS (FR) 2018-12-20 US disclosed
EP-3311438-A1 HIGH-POWER REDOX FLOW BATTERY BASED ON THE CRIII/CRVI REDOX COUPLE AND ITS MEDIATED REGENERATION Chrome Plated Power SAS (FR) 2018-04-25 EP disclosed
WO-2016202950-A1 HIGH-POWER REDOX FLOW BATTERY BASED ON THE CRIII/CRVI REDOX COUPLE AND ITS MEDIATED REGENERATION FINKELSTEIN DAVID ALAN (CH) 2016-12-22 WO disclosed