Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR2 | P30874 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18322930 | 0.90 | SSTR2 (0.43) | SSTR2HRH3CHRM4ACVR1KCNH2 | |
| SCHEMBL18322980 | 0.84 | HRH3 (0.42) | HRH3KCNH2HTR1AHTR2AHTR7 | |
| SCHEMBL18322921 | 0.83 | HRH3 (0.42) | SSTR2HRH3ACVR1KCNH2HTR1A | |
| SCHEMBL18322878 | 0.82 | SSTR2 (0.46) | SSTR2CHRM4TGFBR1ACVR1KCNH2 | |
| SCHEMBL18322841 | 0.81 | HRH3 (0.42) | HRH3KCNH2HTR1AHTR2AHTR7 | |
| SCHEMBL18318480 | 0.81 | PIK3CD (0.44) | SSTR2KCNH2 | |
| SCHEMBL18318171 | 0.78 | NAMPT (0.50) | SSTR2 | |
| SCHEMBL18318170 | 0.78 | NAMPT (0.50) | SSTR2 | |
| SCHEMBL18322938 | 0.75 | CHRNB1 (0.43) | HRH3KCNH2ADRA1A | |
| SCHEMBL18319018 | 0.73 | SSTR2 (0.43) | SSTR2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3310441-A1 | 1, 4-SUBSTITUTED PIPERIDINE DERIVATIVES | Cephalon, Inc. (US) | 2018-04-25 | — | — | EP | disclosed |
| WO-2016205633-A1 | 1, 4-SUBSTITUTED PIPERIDINE DERIVATIVES | CEPHALON, INC. (US) | 2016-12-22 | — | — | WO | disclosed |