Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | FOS | P01100 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18324973 | 0.92 | GAA (0.64) | GAAMEN1MAPTHPGDKMT2A | |
| SCHEMBL16389390 | 0.86 | GAA (0.64) | GAAMEN1MAPTHPGDKMT2A | |
| SCHEMBL29535946 | 0.84 | GAA (0.83) | GAAMEN1MAPTHPGDKMT2A | |
| SCHEMBL1245802 | 0.84 | GAA (0.83) | GAAMEN1MAPTHPGDKMT2A | |
| Vanillyl Alcohol SCHEMBL29408335 | 0.78 | TAAR1 (0.67) | GAATSHRALDH1A1NFKB1TDP1 | |
| Vanillyl Alcohol SCHEMBL27774687 | 0.78 | TAAR1 (0.67) | GAATSHRALDH1A1NFKB1TDP1 | |
| Vanillyl Alcohol SCHEMBL62348 | 0.78 | TAAR1 (0.67) | GAATSHRALDH1A1NFKB1TDP1 | |
| SCHEMBL28447398 | 0.78 | GAA (0.69) | GAAMEN1MAPTHPGDKMT2A | |
| SCHEMBL18325958 | 0.78 | KMT2A (0.64) | GAAMEN1MAPTHPGDKMT2A | |
| SCHEMBL7029677 | 0.77 | CYP3A4 (0.62) | GAAMEN1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160368886-A1 | MULTITARGET HEDGEHOG PATHWAY INHIBITORS AND USES THEREOF | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2016-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368886-A1 | MULTITARGET HEDGEHOG PATHWAY INHIBITORS AND USES THEREOF | SHH, GLI1, SMO | GAA 1875/4885MEN1 387/4885MAPT 3353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.