Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18324957 | 0.89 | CYP3A4 (0.50) | CYP3A4USP2MAPK1SMN1; SMN2APP | |
| SCHEMBL4281069 | 0.79 | CYP3A4 (0.56) | CYP3A4USP2MAPK1SMN1; SMN2APP | |
| SCHEMBL29757572 | 0.78 | CYP3A4 (0.76) | CYP3A4USP2MAPK1SMN1; SMN2APP | |
| SCHEMBL1937218 | 0.78 | CYP3A4 (0.76) | CYP3A4USP2MAPK1SMN1; SMN2APP | |
| SCHEMBL3361677 | 0.78 | APP (0.55) | APPGAAMAPTMEN1KMT2A | |
| SCHEMBL10285344 | 0.77 | AKR1B1 (0.55) | CYP3A4MAPK1APPGAAMEN1 | |
| SCHEMBL18324973 | 0.77 | GAA (0.64) | CYP3A4MAPK1SMN1; SMN2APPHTT | |
| SCHEMBL18324967 | 0.77 | GAA (0.60) | CYP3A4MAPK1APPGAAMAPT | |
| SCHEMBL4408095 | 0.77 | CYP3A4 (0.68) | CYP3A4USP2MAPK1SMN1; SMN2APP | |
| SCHEMBL1515806 | 0.77 | APP (0.47) | CYP3A4APPHTTGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160368886-A1 | MULTITARGET HEDGEHOG PATHWAY INHIBITORS AND USES THEREOF | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2016-12-22 | — | — | US | disclosed |
| US-8227426-B2 | Chiral complexes of ascorbic acid with natural antioxidant and anti-inflammatory ketones including aloe, citrus, ginger, and mango for skin and hair care | ISLAND KINETICS INC. (US) | 2012-07-24 | — | — | US | disclosed |
| US-20120121692-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING CDK INHIBITORS AND METHODS FOR TREATING CANCER | SHANDONG UNIVERSITY (CN) | 2012-05-17 | — | — | US | disclosed |
| US-20110059907-A1 | Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care | ISLAND KINETICS INC. (US) | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059907-A1 | Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care | GLA, LPO, PLOD3 | CYP3A4 510/4885USP2 3211/4885MAPK1 494/4885 |
| US-20160368886-A1 | MULTITARGET HEDGEHOG PATHWAY INHIBITORS AND USES THEREOF | SHH, GLI1, SMO | CYP3A4 4845/4885USP2 1116/4885MAPK1 1388/4885 |
| US-20120121692-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING CDK INHIBITORS AND METHODS FOR TREATING CANCER | CDK6, CDK5, CDK4 | CYP3A4 4112/4885USP2 1719/4885MAPK1 1151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.