Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052872 | 0.88 | ADORA2A (0.44) | ALDH1A1MAPK1 | |
| SCHEMBL7905802 | 0.87 | HDAC1 (0.49) | — | |
| SCHEMBL7063685 | 0.80 | LMNA (0.51) | XDHALDH1A1LMNAL3MBTL1 | |
| SCHEMBL2440388 | 0.78 | LMNA (0.52) | XDHRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13476074 | 0.77 | DEGS1 (0.51) | XDHSPHK2SPHK1RAB9ANPC1 | |
| SCHEMBL7064550 | 0.77 | LMNA (0.47) | XDHRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11018471 | 0.76 | DEGS1 (0.53) | XDHSPHK2SPHK1RAB9ANPC1 | |
| SCHEMBL11016976 | 0.76 | DEGS1 (0.53) | XDHSPHK2SPHK1RAB9ANPC1 | |
| SCHEMBL3626598 | 0.76 | DEGS1 (0.53) | XDHSPHK2SPHK1RAB9ANPC1 | |
| SCHEMBL31260667 | 0.75 | ALDH1A1 (0.45) | ALDH1A1POLBKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016203352-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | MOHAN M ALAPATI (IN) | 2016-12-22 | — | — | WO | disclosed |
| WO-2016203337-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | MOHAN M ALAPATI (IN) | 2016-12-22 | — | — | WO | disclosed |