SCHEMBL18328210

SCHEMBL18328210

O=C(NC(CCl)Cc1ccccc1)OCc1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 2/20 0.74
TACR1 P25103 3/20 0.54
CTSL P07711 3/20 0.53
CTSK P43235 3/20 0.53
CTSB P07858 2/20 0.53
CTSS P25774 2/20 0.53
ALDH1A1 P00352 2/20 0.52
TRPM8 Q7Z2W7 1/20 0.52
ALOX15 P16050 1/20 0.52
CYP3A4 P08684 2/20 0.52
SYK P43405 1/20 0.51
ATM Q13315 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18320645 1.00 CTRB1 (0.74) CTRB1TACR1CTSLCTSKCTSB
SCHEMBL9483693 0.91 CTRB1 (0.62) CTRB1
SCHEMBL2482903 0.86 CTRB1 (0.76) CTRB1TACR1CTSLCTSKCTSB
SCHEMBL1051352 0.86 CTRB1 (0.76) CTRB1TACR1CTSLCTSKCTSB
SCHEMBL2435512 0.86 CTRB1 (0.76) CTRB1TACR1CTSLCTSKCTSB
SCHEMBL10332260 0.85 SYK (0.62) CTRB1CTSLCTSKCTSBCTSS
SCHEMBL8900969 0.85 CTRB1 (0.74) CTRB1TACR1CTSLCTSKCTSB
SCHEMBL6318717 0.85 CTRB1 (0.74) CTRB1TACR1CTSLCTSKCTSB
SCHEMBL6157326 0.85 CTRB1 (0.74) CTRB1TACR1CTSLCTSKCTSB
SCHEMBL14595243 0.85 CTRB1 (0.74) CTRB1TACR1CTSLCTSKCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016202894-A1 METHOD OF CONVERTING ALCOHOL TO HALIDE UNIVERSITAET DES SAARLANDES (DE) 2016-12-22 WO disclosed