Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.74 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.60 |
| ▸ | CASP1 | P29466 | 8/20 | 0.55 |
| ▸ | TACR1 | P25103 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157333 | 1.00 | CTRB1 (0.74) | CTRB1ITGB3ITGA2BCASP1TACR1 | |
| SCHEMBL7136060 | 0.92 | CTRB1 (0.66) | CTRB1CASP1 | |
| SCHEMBL7682035 | 0.90 | CTRB1 (0.72) | CTRB1ITGB3ITGA2BCASP1TACR1 | |
| SCHEMBL7682037 | 0.90 | CTRB1 (0.72) | CTRB1ITGB3ITGA2BCASP1TACR1 | |
| SCHEMBL553905 | 0.88 | CTRB1 (0.61) | CTRB1ITGB3ITGA2BCASP1 | |
| SCHEMBL553906 | 0.88 | CTRB1 (0.61) | CTRB1ITGB3ITGA2BCASP1 | |
| SCHEMBL264008 | 0.88 | CTRB1 (0.61) | CTRB1ITGB3ITGA2BCASP1 | |
| SCHEMBL28184491 | 0.87 | CTRB1 (0.68) | CTRB1ITGB3ITGA2BTACR1CTSL | |
| SCHEMBL7280375 | 0.87 | CTRB1 (0.68) | CTRB1ITGB3ITGA2BTACR1CTSL | |
| SCHEMBL5195145 | 0.87 | CTRB1 (0.59) | CTRB1ITGB3ITGA2BCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1078919-B1 | SYNTHESIS OF ALPHA-AMINO-ALPHA',ALPHA'-DIHALOKETONES AND PROCESS FOR THE PREPARATION OF BETA)-AMINO ACID DERIVATIVES BY THE USE OF THE SAME | KANEKA CORP (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-20030158436-A1 | Synthesis of alpha--amino-alpha, alpha'- dihaloketones and process for the preparation of beta--amino acid derivatives by the use of the same | KANEKA CORPORATION | 2003-08-21 | — | — | US | disclosed |
| US-6573399-B1 | Reacting an alpha -amino acid ester derivative with a base and a dihalomethane | KANEKA CORPORATION (JP) | 2003-06-03 | — | — | US | disclosed |
| EP-1078919-A1 | SYNTHESIS OF $g(a)-AMINO-$g(a)',$g(a)'-DIHALOKETONES AND PROCESS FOR THE PREPARATION OF $g(b)-AMINO ACID DERIVATIVES BY THE USE OF THE SAME | KANEKA CORPORATION (JP) | 2001-02-28 | — | — | EP | disclosed |
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |
| US-4798904-A | ANALGESICS | E. R. SQUIBB & SONS, INC. (US) | 1989-01-17 | — | — | US | disclosed |
| US-4774256-A | MERCAPTO AND ACYLMERCAPTO AMIDES | E. R. SQUIBB & SONS, INC. (US) | 1988-09-27 | — | — | US | disclosed |
| US-4722810-A | Enkephalinase inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1988-02-02 | — | — | US | disclosed |
| EP-0136883-B1 | ENKEPHALINASE INHIBITORS | E.R. Squibb & Sons, Inc. (US) | 1987-11-25 | — | — | EP | disclosed |
| US-4558150-A | ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1985-12-10 | — | — | US | disclosed |
| EP-0158947-A2 | Amino thiol dipeptides | E.R. Squibb & Sons, Inc. (US) | 1985-10-23 | — | — | EP | disclosed |
| US-4521422-A | ANTICONVULSANT, ANTIEPILEPTIC AGENTS, SEDATIVES, MUSCLE RELAXANTS | AMERICAN CYANAMID COMPANY (US) | 1985-06-04 | — | — | US | disclosed |
| EP-0136883-A2 | Enkephalinase inhibitors | E.R. Squibb & Sons, Inc. (US) | 1985-04-10 | — | — | EP | disclosed |
| US-4500518-A | ANALGESICS, HYPTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1985-02-19 | — | — | US | disclosed |
| EP-0129847-A2 | Aryl and heteroaryl[7-(aryl and heteroaryl)-pyrazolo-[1,5-a]-pyrimidin-3-yl]methanones | AMERICAN CYANAMID COMPANY (US) | 1985-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158436-A1 | Synthesis of alpha--amino-alpha, alpha'- dihaloketones and process for the preparation of beta--amino acid derivatives by the use of the same | AADAT, BCAT1, AASDHPPT | CTRB1 4267/4885ITGB3 1735/4885ITGA2B 2250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.