Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | AHR | P35869 | 1/20 | 0.58 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | CETP | P11597 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GALR3 | O60755 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18328467 | 0.88 | MAPK1 (0.69) | MAPK1MEN1KMT2AMAPTNOTUM | |
| SCHEMBL18328462 | 0.86 | MEN1 (0.57) | MAPK1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL18328492 | 0.86 | MAPK1 (0.67) | MAPK1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL18328470 | 0.86 | HPGD (0.61) | MEN1KMT2AMAPTSMN1; SMN2AHR | |
| SCHEMBL18328460 | 0.85 | NOTUM (0.65) | MAPK1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL18328450 | 0.85 | MEN1 (0.56) | MAPK1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL26343122 | 0.85 | MAPT (0.65) | MAPK1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL18328495 | 0.85 | CNR1 (0.53) | MAPK1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL18328468 | 0.85 | KMT2A (0.61) | MAPK1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL18328475 | 0.82 | MEN1 (0.55) | MAPK1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9751851-B2 | Molecules and compositions that inhibit gram negative bacteria and their uses | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2017-09-05 | — | — | US | disclosed |
| US-20160368892-A1 | MOLECULES AND COMPOSITIONS THAT INHIBIT GRAM NEGATIVE BACTERIA AND THEIR USES | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368892-A1 | MOLECULES AND COMPOSITIONS THAT INHIBIT GRAM NEGATIVE BACTERIA AND THEIR USES | BLVRB, PGLS, GRHPR | MAPK1 1169/4885MEN1 4766/4885KMT2A 4247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.