SCHEMBL18328596

SCHEMBL18328596

CCCCCC[C@H](O)C/C=C\CCCCCCCC(=O)OCC(COC(=O)CCCCCCC/C=C\C[C@H](O)CCCCCC)OC(=O)CCCCCCC/C=C\C[C@H](O)CCCCCC

nearest known ligand 0.73

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 3/20 0.70
PRKCE Q02156 2/20 0.70
PRKCQ Q04759 2/20 0.70
PRKCD Q05655 2/20 0.70
ALDH1A1 P00352 1/20 0.64
LMNA P02545 1/20 0.64
FFAR1 O14842 1/20 0.63
FFAR4 Q5NUL3 1/20 0.63
DGKA P23743 1/20 0.62
SELP P16109 1/20 0.60
LPAR1 Q92633 4/20 0.56
FAAH O00519 1/20 0.56
CES2 O00748 1/20 0.56
ENPP2 Q13822 1/20 0.56
LPAR4 Q99677 1/20 0.56
LPAR5 Q9H1C0 1/20 0.56
LPAR2 Q9HBW0 1/20 0.56
LPAR3 Q9UBY5 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8734221 1.00 PRKCA (0.70) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL17518704 1.00 PRKCA (0.70) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL11946617 1.00 PRKCA (0.70) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL12836586 1.00 PRKCA (0.70) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL23962839 1.00 PRKCA (0.70) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL23963008 1.00 PRKCA (0.70) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL2770151 1.00 PRKCA (0.70) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL12939325 1.00 PRKCA (0.70) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL5414095 1.00 PRKCA (0.70) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL14105342 1.00 PRKCA (0.70) PRKCAPRKCEPRKCQPRKCDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160367678-A1 BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF LAUREN SCIENCES LLC (US) 2016-12-22 US disclosed
US-20160367678-A1 BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF LAUREN SCIENCES LLC (US) 2016-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160367678-A1 BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF GFRA2, GFRA1, NGF PRKCA 4302/4885PRKCE 4637/4885PRKCQ 4660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.