SCHEMBL18328847

SCHEMBL18328847

C=CC(=O)OCOc1ccc(C#CC(=O)Oc2ccc(-c3ccc(OCOC(=O)C=C)cc3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.40
FFAR1 O14842 6/20 0.36
ACACB O00763 2/20 0.34
PPARD Q03181 1/20 0.34
PPARA Q07869 1/20 0.34
MMP2 P08253 4/20 0.33
PDE6D O43924 1/20 0.32
MMP3 P08254 2/20 0.31
MMP1 P03956 1/20 0.31
MMP9 P14780 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12733804 0.96 THRB (0.42) THRBFFAR1ACACBPPARDPPARA
SCHEMBL15397361 0.93 FFAR1 (0.39) THRBFFAR1ACACBPPARDPPARA
SCHEMBL19759238 0.91 THRB (0.36) THRBFFAR1ACACBPPARDPPARA
SCHEMBL16426195 0.89 FFAR1 (0.41) THRBFFAR1ACACBPPARDPPARA
SCHEMBL19759239 0.87 THRB (0.39) THRBFFAR1ACACBPPARDPPARA
SCHEMBL19929427 0.85 THRB (0.36) THRBFFAR1ACACB
SCHEMBL19759391 0.85 FFAR1 (0.33) THRBFFAR1ACACBPPARDPPARA
SCHEMBL19929426 0.84 FFAR1 (0.37) THRBFFAR1ACACBPPARDPPARA
SCHEMBL12733803 0.83 THRB (0.50) THRBFFAR1ACACB
SCHEMBL11917942 0.83 THRB (0.53) THRBMMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180066189-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC CORPORATION (JP) 2018-03-08 US disclosed
US-20160370626-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-12-22 US disclosed