SCHEMBL12733804

SCHEMBL12733804

C=CC(=O)OCOc1ccc(C#CC(=O)Oc2ccc(OCOC(=O)C=C)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.42
ACACB O00763 2/20 0.36
FFAR1 O14842 7/20 0.35
TSHR P16473 5/20 0.32
HPGD P15428 1/20 0.32
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31
ALDH1A1 P00352 4/20 0.31
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
CYP3A4 P08684 1/20 0.31
HSD17B10 Q99714 1/20 0.31
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18328847 0.96 THRB (0.40) THRBACACBFFAR1PPARDPPARA
SCHEMBL16426195 0.93 FFAR1 (0.41) THRBACACBFFAR1PPARDPPARA
SCHEMBL19759239 0.91 THRB (0.39) THRBACACBFFAR1PPARDPPARA
SCHEMBL15397361 0.89 FFAR1 (0.39) THRBACACBFFAR1PPARDPPARA
SCHEMBL19929427 0.89 THRB (0.36) THRBACACBFFAR1
SCHEMBL19759238 0.88 THRB (0.36) THRBACACBFFAR1PPARDPPARA
SCHEMBL12733803 0.87 THRB (0.50) THRBACACBFFAR1TSHRHPGD
SCHEMBL12604045 0.85 THRB (0.49) THRBACACBFFAR1TSHRHPGD
SCHEMBL19759395 0.84 THRB (0.36) THRBACACB
SCHEMBL25486151 0.83 THRB (0.47) THRBACACBFFAR1TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9927625-B2 Birefringent lens material for stereoscopic image display device and method for producing birefringent lens for stereoscopic image display device DIC CORPORATION (JP) 2018-03-27 US disclosed
US-20180066189-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC CORPORATION (JP) 2018-03-08 US disclosed
US-20160370626-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-12-22 US disclosed
US-20130309411-A1 BIREFRINGENT LENS MATERIAL FOR STEREOSCOPIC IMAGE DISPLAY DEVICE AND METHOD FOR PRODUCING BIREFRINGENT LENS FOR STEREOSCOPIC IMAGE DISPLAY DEVICE DIC CORPORATION (JP) 2013-11-21 US disclosed
US-7919009-B2 Polymerizable compounds and polymerizable compositions ADEKA CORPORATION (JP) 2011-04-05 US disclosed
US-7910021-B2 Polymerizable optical active compound and polymerizable composition containing the same ADEKA CORPORATION (JP) 2011-03-22 US disclosed
US-20100032620-A1 POLYMERIZABLE OPTICAL ACTIVE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE SAME ADEKA CORPORATION (JP) 2010-02-11 US disclosed
US-20100032621-A1 POLYMERIZABLE COMPOUNDS AND POLYMERIZABLE COMPOSITIONS ADEKA CORPORATION (JP) 2010-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100032620-A1 POLYMERIZABLE OPTICAL ACTIVE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE SAME C1S, PYM1, MCCC2 THRB 3247/4885ACACB 364/4885FFAR1 4301/4885
US-20100032621-A1 POLYMERIZABLE COMPOUNDS AND POLYMERIZABLE COMPOSITIONS CHRM1, CHRM2, CCNE1 THRB 4880/4885ACACB 3347/4885FFAR1 3521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.