SCHEMBL19759239

SCHEMBL19759239

C=CC(=O)Cc1ccc(C#CC(=O)Oc2ccc(OCOC(=O)C=C)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.39
ACACB O00763 3/20 0.35
FFAR1 O14842 5/20 0.34
PPARD Q03181 2/20 0.31
PPARA Q07869 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19759238 0.97 THRB (0.36) THRBACACBFFAR1PPARDPPARA
SCHEMBL12733804 0.91 THRB (0.42) THRBACACBFFAR1PPARDPPARA
SCHEMBL19771197 0.90 THRB (0.32) THRBACACBFFAR1
SCHEMBL16426195 0.88 FFAR1 (0.41) THRBACACBFFAR1PPARDPPARA
SCHEMBL19771196 0.88 FFAR1 (0.34) THRBACACBFFAR1PPARDPPARA
SCHEMBL18328847 0.87 THRB (0.40) THRBACACBFFAR1PPARDPPARA
SCHEMBL15397361 0.85 FFAR1 (0.39) THRBACACBFFAR1PPARDPPARA
SCHEMBL19929427 0.81 THRB (0.36) THRBACACBFFAR1
SCHEMBL12733803 0.78 THRB (0.50) THRBACACBFFAR1
SCHEMBL19929428 0.78 FFAR1 (0.37) THRBACACBFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11697695-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2023-07-11 US disclosed
US-20180112022-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC MATERIAL DIC CORPORATION (JP) 2018-04-26 US disclosed
US-20180016502-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC CORPORATION (JP) 2018-01-18 US disclosed
US-20180002459-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC CORPORATION (JP) 2018-01-04 US disclosed
US-20180002460-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC CORPORATION (JP) 2018-01-04 US disclosed