SCHEMBL18329397

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18329398	0.80	WDR5 (0.65)	PDCD1CD274WDR5ALDH1A1KDM4E
	SCHEMBL18329393	0.78	WDR5 (0.48)	PDCD1CD274WDR5ALDH1A1KDM4E
	SCHEMBL2813860	0.77	PDCD1 (0.66)	PDCD1CD274WDR5ALDH1A1KDM4E
	SCHEMBL18329399	0.76	PDCD1 (0.49)	PDCD1CD274WDR5ALDH1A1KDM4E
	SCHEMBL15933673	0.76	PDCD1 (0.51)	PDCD1CD274WDR5GABRA3TLR9
	SCHEMBL929019	0.75	PDCD1 (0.56)	PDCD1CD274WDR5HTR7TLR9
	SCHEMBL18329402	0.72	NPC1 (0.67)	PDCD1CD274WDR5ALDH1A1KDM4E
	SCHEMBL2812580	0.72	PDCD1 (0.62)	PDCD1CD274ALDH1A1KDM4ELMNA
	SCHEMBL18329424	0.72	WDR5 (0.45)	PDCD1CD274WDR5ALDH1A1KDM4E
	SCHEMBL10749515	0.71	PDCD1 (0.49)	PDCD1CD274WDR5TLR9TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.