Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26635590 | 0.90 | GPR119 (0.47) | GPR119KDM4EPKMNPC1ALDH1A1 | |
| SCHEMBL26637294 | 0.90 | GPR119 (0.47) | GPR119KDM4EPKMNPC1ALDH1A1 | |
| SCHEMBL26636540 | 0.90 | GPR119 (0.47) | GPR119KDM4EPKMNPC1ALDH1A1 | |
| SCHEMBL26636545 | 0.90 | GPR119 (0.47) | GPR119KDM4EPKMNPC1ALDH1A1 | |
| SCHEMBL26635583 | 0.90 | GPR119 (0.47) | GPR119KDM4EPKMNPC1ALDH1A1 | |
| SCHEMBL2560698 | 0.85 | GPR119 (0.46) | GPR119KDM4EPKMALDH1A1MAPT | |
| SCHEMBL2557716 | 0.83 | EED (0.46) | GPR119KDM4EPKMNPC1ALDH1A1 | |
| SCHEMBL1295724 | 0.81 | GPR119 (0.62) | GPR119FAAH | |
| SCHEMBL31574979 | 0.81 | EPHX2 (0.49) | GPR119EPHX2KDM4EPKMALDH1A1 | |
| SCHEMBL31574733 | 0.81 | EPHX2 (0.49) | GPR119EPHX2KDM4EPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321297-A1 | PIPERIDINYL GPCR AGONISTS | Prosidion Limited (GB) | 2011-05-18 | — | — | EP | disclosed |