Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.46 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.46 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.46 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.46 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | YAP1 | P46937 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560698 | 0.90 | GPR119 (0.46) | GPR119ALDH1A1KDM4EPKMYAP1 | |
| SCHEMBL26636540 | 0.85 | GPR119 (0.47) | GPR119ALDH1A1KDM4EPKMYAP1 | |
| SCHEMBL26637294 | 0.85 | GPR119 (0.47) | GPR119ALDH1A1KDM4EPKMYAP1 | |
| SCHEMBL26635583 | 0.85 | GPR119 (0.47) | GPR119ALDH1A1KDM4EPKMYAP1 | |
| SCHEMBL26636545 | 0.85 | GPR119 (0.47) | GPR119ALDH1A1KDM4EPKMYAP1 | |
| SCHEMBL26635590 | 0.85 | GPR119 (0.47) | GPR119ALDH1A1KDM4EPKMYAP1 | |
| SCHEMBL1295322 | 0.84 | GPR119 (0.61) | GPR119 | |
| SCHEMBL1833006 | 0.83 | GPR119 (0.44) | GPR119ALDH1A1KDM4EPKMNPC1 | |
| SCHEMBL1296099 | 0.81 | EED (0.48) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL1847797 | 0.78 | GPR119 (0.69) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011128394-A1 | 3-SUBSTITUTED 5-(PYRROLIDINE-1-CARBONYL) PYRROLIDINE AND ITS DERIVATIVES FOR USE IN THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2011-10-20 | — | — | WO | disclosed |