Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | USP5 | P45974 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18332391 | 0.89 | PTGDR2 (0.39) | ALOX5NOD2NOD1PTGDR2ALOX12 | |
| SCHEMBL18331686 | 0.89 | ALOX5 (0.40) | ALOX5NOD2NOD1PTGDR2ALOX12 | |
| SCHEMBL20584087 | 0.88 | PTGDR2 (0.38) | ALOX5NOD2NOD1PTGDR2ALOX12 | |
| SCHEMBL10003089 | 0.80 | PTGDR2 (0.39) | ALOX5NOD2NOD1PTGDR2L3MBTL1 | |
| SCHEMBL18332163 | 0.80 | HRH3 (0.41) | ALOX5NOD2NOD1PTGDR2L3MBTL1 | |
| SCHEMBL10004537 | 0.78 | HRH3 (0.41) | ALOX5NOD2NOD1PTGDR2L3MBTL1 | |
| SCHEMBL18332156 | 0.78 | NOD1 (0.44) | ALOX5NOD2NOD1PTGDR2PPARG | |
| SCHEMBL10002843 | 0.77 | NOD2 (0.44) | ALOX5NOD2NOD1PTGDR2PPARG | |
| SCHEMBL10003990 | 0.77 | NOD2 (0.44) | ALOX5NOD2NOD1PTGDR2PPARG | |
| SCHEMBL10003707 | 0.77 | ALOX5 (0.41) | ALOX5NOD2NOD1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016204261-A1 | AMINOPYRAZOLE DERIVATIVES | 中外製薬株式会社 | 2016-12-22 | — | — | WO | disclosed |