Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | CMA1 | P23946 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31513486 | 0.87 | PDK2 (0.44) | PDK2TDP2 | |
| SCHEMBL23568056 | 0.87 | PDK2 (0.44) | PDK2TDP2 | |
| SCHEMBL23568673 | 0.87 | PDK2 (0.44) | PDK2TDP2 | |
| SCHEMBL29404184 | 0.82 | PDK2 (0.47) | PDK2TDP2AKR1A1AKR1B1S100A4 | |
| SCHEMBL437007 | 0.82 | PDK2 (0.47) | PDK2TDP2AKR1A1AKR1B1S100A4 | |
| SCHEMBL21005872 | 0.78 | ALDH1A1 (0.33) | CYP2A6 | |
| SCHEMBL27638900 | 0.78 | PDK2 (0.37) | PDK2TDP2AKR1A1AKR1B1S100A4 | |
| SCHEMBL12027473 | 0.77 | CES1 (0.38) | — | |
| SCHEMBL23568686 | 0.75 | TDP2 (0.33) | PDK2TDP2S100A4CA1CA2 | |
| SCHEMBL21939620 | 0.74 | PDK2 (0.41) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10727414-B2 | Functional hole transport materials for optoelectronic and/or electrochemical devices | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2020-07-28 | — | — | US | disclosed |
| US-10727414-B2 | Functional hole transport materials for optoelectronic and/or electrochemical devices | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2020-07-28 | — | — | US | disclosed |
| US-20180190911-A1 | FUNCTIONAL HOLE TRANSPORT MATERIALS FOR OPTOELECTRONIC AND/OR ELECTROCHEMICAL DEVICES | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2018-07-05 | — | — | US | disclosed |
| US-20180190911-A1 | FUNCTIONAL HOLE TRANSPORT MATERIALS FOR OPTOELECTRONIC AND/OR ELECTROCHEMICAL DEVICES | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2018-07-05 | — | — | US | disclosed |
| WO-2016207775-A1 | FUNCTIONAL HOLE TRANSPORT MATERIALS FOR OPTOELECTRONIC AND/OR ELECTROCHEMICAL DEVICES | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2016-12-29 | — | — | WO | disclosed |
| EP-3109912-A1 | FUNCTIONAL HOLE TRANSPORT MATERIALS FOR OPTOELECTRONIC AND /OR ELECTROCHEMICAL DEVICES | Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) | 2016-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180190911-A1 | FUNCTIONAL HOLE TRANSPORT MATERIALS FOR OPTOELECTRONIC AND/OR ELECTROCHEMICAL DEVICES | SLCO2A1, SLCO4C1, SLCO1A2 | PDK2 2455/4885TDP2 3993/4885AKR1A1 1183/4885 |
| US-10727414-B2 | Functional hole transport materials for optoelectronic and/or electrochemical devices | SLCO2A1, SLCO4C1, SLCO1A2 | PDK2 2455/4885TDP2 3993/4885AKR1A1 1183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.