Hypophosphorous Acid

Hypophosphorous Acid

SCHEMBL3367718

O=[PH2]O.OC(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.52
CYP1A2 P05177 1/20 0.50
SRR Q9GZT4 2/20 0.47
ALPI P09923 1/20 0.47
PKM P14618 1/20 0.47
PTGS1 P23219 1/20 0.47
XIAP P98170 1/20 0.47
SLC7A5 Q01650 1/20 0.47
ALPL P05186 1/20 0.46
POLB P06746 1/20 0.46
ALPG P10696 1/20 0.46
MDM2 Q00987 1/20 0.45
TRPV1 Q8NER1 1/20 0.45
EPHX1 P07099 1/20 0.44
TSHR P16473 1/20 0.44
LAP3 P28838 3/20 0.44
CPA1 P15085 2/20 0.44
CPA3 P15088 2/20 0.44
ANPEP P15144 1/20 0.44
FOLH1 Q04609 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1833635 0.88 TRPA1 (0.55) TRPA1CYP1A2SRRALPIPKM
Ammonia Solution, Strong SCHEMBL29021310 0.85 TRPA1 (0.53) TRPA1CYP1A2SRRALPIPKM
SCHEMBL29061185 0.79 SRR (0.53) TRPA1CYP1A2SRRALPIPKM
Nitric Acid SCHEMBL9873353 0.78 CPA1 (0.53) TRPA1CYP1A2SRRALPIPKM
Benzoic Acid SCHEMBL10392449 0.78 DAO (0.58) TRPA1CYP1A2SRRALPIPKM
SCHEMBL5105980 0.78 TRPA1 (0.52) TRPA1CYP1A2SRRALPIPKM
SCHEMBL3091836 0.78 TRPA1 (0.52) TRPA1CYP1A2SRRALPIPKM
SCHEMBL3091848 0.78 TRPA1 (0.52) TRPA1CYP1A2SRRALPIPKM
Benzyl Alcohol SCHEMBL8639982 0.78 TSHR (0.74) CYP1A2TSHR
SCHEMBL2211027 0.76 TRPA1 (0.56) TRPA1CYP1A2SRRALPIPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010056795-A1 NOVEL SYNTHETIC DINUCLEOSIDE POLYPHOSPHATE ANALOGS AND THEIR USE AS NEW THERAPEUTIC AND/OR DIAGNOSTIC MODALITIES ZATA PHARMACEUTICALS, INC. (US) 2010-05-20 WO disclosed