SCHEMBL1833758

SCHEMBL1833758

C=CC(=O)Oc1ccccc1C(C)(C)c1ccccc1OC(=O)C=C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.49
THRA P10827 1/20 0.49
ATM Q13315 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
KDM4E B2RXH2 4/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
BCHE P06276 1/20 0.38
ELANE P08246 2/20 0.38
TYMS P04818 1/20 0.38
ALDH1A1 P00352 3/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
GAA P10253 1/20 0.34
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
RXRG P48443 1/20 0.34
LIG1 P18858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10883978 0.91 ATM (0.46) THRBTHRAATMTDP1KDM4E
SCHEMBL34006 0.90 TDP1 (0.58) THRBTHRAATMTDP1KDM4E
SCHEMBL30438185 0.90 TDP1 (0.58) THRBTHRAATMTDP1KDM4E
Hydrochloric Acid SCHEMBL17698428 0.85 THRB (0.46) THRBTHRAATMTDP1KDM4E
SCHEMBL25367674 0.84 THRB (0.51) THRBTHRAATMTDP1KDM4E
SCHEMBL28818569 0.83 THRB (0.44) THRBTHRAATMTDP1KDM4E
SCHEMBL27663715 0.83 THRA (0.46) THRBTHRAATMTDP1KDM4E
SCHEMBL29413361 0.81 THRB (0.56) THRBTHRATDP1KDM4EMAPT
SCHEMBL3841280 0.81 THRB (0.56) THRBTHRATDP1KDM4EMAPT
SCHEMBL14673602 0.80 THRB (0.43) THRBTHRAATMTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6352782-B1 None US claimed
EP-1834975-B1 Thermosetting poly(phenylene ether) SABIC INNOVATIVE PLASTICS IP (NL) 2011-05-11 EP claimed
US-6617398-B2 Forming laminate; curing; cladding with copper; printed circuits GENERAL ELECTRIC COMPANY 2003-09-09 US claimed
US-20020028337-A1 Poly (phenylene ether) - polyvinyl thermosetting resin SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2002-03-07 US claimed
US-6352782-B2 REACTING A POLYPHENYLENE ETHER CONTAINING HYDROXY GROUPS THAT HAVE BEEN CAPPED WITH A COMPOUND CONTAINING ETHYLENICALLY UNSATURATION WITH A CURABLE UNSATURATED MONOMER CAPABLE OF REACTING WITH ETHYLENICALLY UNSATURATED COMPOUND GENERAL ELECTRIC COMPANY 2002-03-05 US claimed
US-6352782-B1 None US disclosed
US-10752833-B2 Optical element for correcting color blindness NITTO DENKO CORPORATION (JP) 2020-08-25 US disclosed
US-20190194535-A1 OPTICAL ELEMENT FOR CORRECTING COLOR BLINDNESS NITTO DENKO CORPORATION (JP) 2019-06-27 US disclosed
US-10119070-B2 Optical element for correcting color blindness NITTO DENKO CORPORATION (JP) 2018-11-06 US disclosed
US-9885883-B2 Optical element for correcting color blindness NITTO DENKO CORPORATION (JP) 2018-02-06 US disclosed
US-20170088771-A1 OPTICAL ELEMENT FOR CORRECTING COLOR BLINDNESS NITTO DENKO CORPORATION (JP) 2017-03-30 US disclosed
EP-2951620-B1 OPTICAL ELEMENT FOR CORRECTING COLOR BLINDNESS NITTO DENKO CORP (JP) 2017-03-01 EP disclosed
EP-1265946-A1 POLY(PHENYLENE ETHER) - POLYVINYL THERMOSETTING RESIN GENERAL ELECTRIC COMPANY (US) 2002-12-18 EP disclosed
US-20020028337-A1 Poly (phenylene ether) - polyvinyl thermosetting resin SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2002-03-07 US disclosed
US-6352782-B2 REACTING A POLYPHENYLENE ETHER CONTAINING HYDROXY GROUPS THAT HAVE BEEN CAPPED WITH A COMPOUND CONTAINING ETHYLENICALLY UNSATURATION WITH A CURABLE UNSATURATED MONOMER CAPABLE OF REACTING WITH ETHYLENICALLY UNSATURATED COMPOUND GENERAL ELECTRIC COMPANY 2002-03-05 US disclosed
US-20010053450-A1 POLY (PHENYLENE ETHER) - POLYVINYL THERMOSETTING RESIN SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2001-12-20 US disclosed
WO-2001040354-A1 POLY(PHENYLENE ETHER) - POLYVINYL THERMOSETTING RESIN GENERAL ELECTRIC COMPANY (US) 2001-06-07 WO disclosed
US-4394494-A DIURETHANE TETRAACRYLATES AS POLYMERIZABLE MONOMERS LION CORPORATION (JP) 1983-07-19 US disclosed
US-4388421-A PRIMERS LION CORPORATION (JP) 1983-06-14 US disclosed
US-4383052-A 1-Methacryloxyethane-1,1-diphosphonic acid and its salts and dental adhesive composition containing same LION CORPORATION (JP) 1983-05-10 US disclosed