SCHEMBL581128

SCHEMBL581128

Nc1nc(Nc2ccccc2)nc(N(c2ccccc2)c2ccccc2)n1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.54
NPC1 O15118 4/20 0.53
RAB9A P51151 4/20 0.53
KMT2A Q03164 3/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
HTT P42858 2/20 0.53
TSHR P16473 2/20 0.53
LMNA P02545 1/20 0.53
JAK2 O60674 1/20 0.53
ALDH1A1 P00352 3/20 0.51
PKM P14618 2/20 0.50
BCL6 P41182 1/20 0.50
KDM4E B2RXH2 2/20 0.47
MEN1 O00255 2/20 0.47
GAA P10253 1/20 0.47
KCNH3 Q9ULD8 1/20 0.46
CDK9 P50750 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
CYP1A2 P05177 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31528560 1.00 MAPT (0.54) MAPTNPC1RAB9AKMT2ASMN1; SMN2
SCHEMBL11655354 0.90 CDK9 (0.53) MAPTNPC1RAB9AKMT2ASMN1; SMN2
SCHEMBL11509348 0.88 ALDH1A1 (0.59) MAPTKMT2ALMNAALDH1A1KDM4E
SCHEMBL28536474 0.84 CA1 (0.44) MAPTNPC1RAB9AKMT2ASMN1; SMN2
SCHEMBL11589382 0.84 MAPT (0.48) MAPTNPC1RAB9AKMT2ASMN1; SMN2
SCHEMBL14869409 0.82 ALDH1A1 (0.77) MAPTNPC1RAB9AKMT2ASMN1; SMN2
SCHEMBL8612276 0.81 RAB9A (0.55) MAPTNPC1RAB9AKMT2ASMN1; SMN2
SCHEMBL11655357 0.81 NPC1 (0.50) MAPTNPC1RAB9AKMT2ASMN1; SMN2
SCHEMBL9621510 0.81 MAPT (0.44) MAPTNPC1RAB9AKMT2ASMN1; SMN2
SCHEMBL28451008 0.81 MAPT (0.66) MAPTNPC1RAB9AKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114685933-B Polyformaldehyde composite material and preparation method and application thereof 江苏金发科技新材料有限公司 2024-01-02 CN claimed
CN-114685933-A Polyformaldehyde composite material and preparation method and application thereof 江苏金发科技新材料有限公司 2022-07-01 CN claimed
US-9745515-B2 Fire resistant material COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2017-08-29 US claimed
EP-1576073-B1 FIRE RESISTANT MATERIAL COMMW SCIENT IND RES ORG (AU) 2012-02-15 EP claimed
US-20110281981-A1 FIRE RESISTANT MATERIAL THE BOEING COMPANY 2011-11-17 US claimed
CN-100567457-C Refractory materials COMMW SCIENT IND RES ORG BOEIN (AU) 2009-12-09 CN claimed
WO-2004039916-A9 FIRE RESISTANT MATERIAL COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2009-10-29 WO claimed
EP-1576073-A4 FIRE RESISTANT MATERIAL COMMW SCIENT IND RES ORG (AU) 2008-06-25 EP claimed
US-20070194289-A1 Fire resistant material Commonwealth Scientific & Industrial Research Org. a Australian Corporation 2007-08-23 US claimed
CN-1732246-A Fire resistant material COMMW SCIENT IND RES ORG (AU) 2006-02-08 CN claimed
EP-1576073-A1 FIRE RESISTANT MATERIAL COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2005-09-21 EP claimed
WO-2004039916-A1 FIRE RESISTANT MATERIAL COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-05-13 WO claimed
CN-119301194-A Hydrophilic composition 信越化学工业株式会社 2025-01-10 CN disclosed
CN-113754983-B Resin composition 旭化成株式会社 2024-12-06 CN disclosed
CN-118055975-A Polyacetal resin composition 宝理塑料株式会社 2024-05-17 CN disclosed
CN-118055976-A Polyacetal resin composition 宝理塑料株式会社 2024-05-17 CN disclosed
US-4095557-A Apparatus for making electrical coils using patterned dry resin coated sheet insulation WESTINGHOUSE ELECTRIC CORP. (US) 1978-06-20 US disclosed
US-3988292-A A TRIAZINE DERIVATIVE TEIJIN LIMITED (JA) 1976-10-26 US disclosed
US-3974302-A Method of making patterned dry resin coated sheet insulation WESTINGHOUSE ELECTRIC CORPORATION (US) 1976-08-10 US disclosed
US-3934332-A Method of making electrical coils having improved strength and oil permeability WESTINGHOUSE ELECTRIC CORPORATION (US) 1976-01-27 US disclosed