Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1693088 | 0.89 | RAB9A (0.44) | RAB9AGAANOS3NOS2THRB | |
| SCHEMBL13503893 | 0.88 | RAB9A (0.49) | RAB9AGAANOS3NOS2THRB | |
| SCHEMBL19434335 | 0.88 | GAA (0.59) | GAANOS3NOS2THRBATM | |
| SCHEMBL4596054 | 0.84 | GAA (0.45) | RAB9AGAANOS3NOS2THRB | |
| SCHEMBL704010 | 0.84 | RAB9A (0.51) | RAB9AGAANOS3NOS2THRB | |
| SCHEMBL1693216 | 0.83 | RAB9A (0.48) | RAB9AGAANOS3NOS2THRB | |
| SCHEMBL10089204 | 0.83 | RAB9A (0.48) | RAB9AGAANOS3NOS2THRB | |
| SCHEMBL4595366 | 0.83 | RAB9A (0.43) | RAB9AGAANOS3NOS2THRB | |
| SCHEMBL794087 | 0.83 | RAB9A (0.50) | RAB9AGAANOS3NOS2THRB | |
| SCHEMBL8262844 | 0.83 | RAB9A (0.50) | RAB9AGAANOS3NOS2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2320910-A1 | CHEMICAL COMPOUNDS AND USES | GlaxoSmithKline LLC (US) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010014593-A1 | CHEMICAL COMPOUNDS AND USES | SMITHKLINE BEECHAM CORPORATION (US) | 2010-02-04 | — | — | WO | disclosed |