Methacrylic Acid

Methacrylic Acid

SCHEMBL183419

C=C(C)C(=O)O.O=C1CCCN1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.60
CRBN Q96SW2 3/20 0.52
FKBP5 Q13451 1/20 0.52
KDM4E B2RXH2 3/20 0.38
GAA P10253 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 2/20 0.33
ALDH1A1 P00352 1/20 0.33
GFER P55789 1/20 0.33
KMT2A Q03164 1/20 0.32
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL27631941 0.98 OR51E2 (0.58) OR51E2CRBNFKBP5KDM4EGAA
Methacrylic Acid SCHEMBL28219344 0.96 OR51E2 (0.56) OR51E2CRBNFKBP5KDM4EGAA
Caprolactam SCHEMBL4163313 0.92 CRBN (0.59) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL27544296 0.88 OR51E2 (0.65) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL2155488 0.87 OR51E2 (0.71) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL28258038 0.87 OR51E2 (0.71) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL1458792 0.86 OR51E2 (0.58) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL28209360 0.86 OR51E2 (0.62) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL27605240 0.85 OR51E2 (0.68) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL17698402 0.85 OR51E2 (0.75) OR51E2CRBNFKBP5KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116490536-A Biodegradable delivery particles 恩盖普有限公司 2023-07-25 CN claimed
EP-2551102-B1 Self-stick foam adhesive 3M INNOVATIVE PROPERTIES CO (US) 2014-12-03 EP claimed
US-20140147610-A1 SELF-STICK FOAM ADHESIVE 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-05-29 US claimed
WO-2009099539-A2 (METH)ACRYLATE SURFACES FOR CELL CULTURE, METHODS OF MAKING AND USING THE SURFACES CORNING INCORPORATED (US) 2009-08-13 WO claimed
US-20090191634-A1 (METH)ACRYLATE SURFACES FOR CELL CULTURE, METHODS OF MAKING AND USING THE SURFACES GERON CORPORATION 2009-07-30 US claimed
EP-1268621-B1 SURFACE TREATMENT OF SILICONE MEDICAL DEVICES BAUSCH & LOMB (US) 2005-11-23 EP claimed
CN-1186330-C Polymerizable hydrophilio ultraviolet light absorbing manomers PHARMACIA & UPJOHN BV (NL) 2005-01-26 CN claimed
US-20030235604-A1 Renewable surface treatment of silicone medical devices with reactive hydrophilic polymers BAUSCH & LOMB INCORPORATED (US) 2003-12-25 US claimed
US-20030068433-A1 Method for applying polymeric lens coating BAUSCH & LOMB INCORPORATED 2003-04-10 US claimed
CN-1103786-C High refractive index hydrogels prepared from polymers and copolymers of N-benzyl-N-methylacrylamide PHARMACIA IOVISION INC (US) 2003-03-26 CN claimed
EP-1268621-A1 SURFACE TREATMENT OF SILICONE MEDICAL DEVICES BAUSCH & LOMB INCORPORATED (US) 2003-01-02 EP claimed
WO-2001074932-A1 SURFACE TREATMENT OF SILICONE MEDICAL DEVICES BAUSCH & LOMB INCORPORATED (US) 2001-10-11 WO claimed
CN-1300283-A Polymerizable hydrophilio ultraviolet light absorbing manomers PHARMACIA & UPJOHN BV (NL) 2001-06-20 CN claimed
CN-1219179-A High refractive index hydrogels prepared from polymers and copolymers of N-benzyl-N-methylacrylamide PHARMACIA IOVISION INC (US) 1999-06-09 CN claimed
US-20220153901-A1 Poly Acrylate and Poly(Beta-Amino Ester) Capsules with Enhanced Degradability Encapsys,LLC (US) 2022-05-19 US disclosed
US-10844154-B2 Proliferous copolymers comprising lactamic moieties ISP INVESTMENTS LLC (US) 2020-11-24 US disclosed
CN-110461375-A HYDROGEL COMPOSITIONS BONDED TO POLYMERIC SUBSTRATES 3M INNOVATIVE PROPERTIES CO 2019-11-15 CN disclosed
US-4980086-A COMPRISING A CYANOACRYLATE ESTER, ELECTROCONDUCTIVE POWDER, THERMOCONDUCTIVE POWDER, ELECTRON ACCEPTOR OR A COORDINATION COMPLEX AND ELECTRON DONOR; ADHESIVE, COATIG, PAINT, POTTING TOAGOSEI CHEMICAL INDUSTRY, CO., LTD. (JP) 1990-12-25 US disclosed
US-4749761-A FOR CONTACT LENSES-CROSSLINKED COPOLYMER OF N-VINYL-2-PYRROLIDONE AND ACRYLIC ESTER SMITH & NEPHEW ASSOCIATED COMPANIES P.L.C. (GB) 1988-06-07 US disclosed
US-4138382-A WATER SOLUBLE VINYL CONSTITUENT AND AN OLEFINIC HYDROLYZABLE SILANE DOW CORNING CORPORATION (US) 1979-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10844154-B2 Proliferous copolymers comprising lactamic moieties PCNA, MKI67, CCNA1 OR51E2 4395/4885CRBN 302/4885FKBP5 180/4885
US-20220153901-A1 Poly Acrylate and Poly(Beta-Amino Ester) Capsules with Enhanced Degradability APEH, PDGFA, ABHD6 OR51E2 1906/4885CRBN 2951/4885FKBP5 4620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.