Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26205633 | 0.86 | HSD17B10 (0.48) | HSD17B10KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL29168975 | 0.80 | HSD17B10 (0.50) | HSD17B10KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL29168977 | 0.80 | HSD17B10 (0.50) | HSD17B10KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL4970580 | 0.79 | MAOB (0.50) | HSD17B10KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL7978367 | 0.77 | HSD17B10 (0.58) | HSD17B10KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL19384259 | 0.77 | LMNA (0.61) | HSD17B10KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL29893918 | 0.77 | HSD17B10 (0.58) | HSD17B10KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL19384428 | 0.77 | LMNA (0.61) | HSD17B10KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL19384288 | 0.77 | LMNA (0.61) | HSD17B10KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL9324039 | 0.77 | MAOB (0.51) | HSD17B10KDM4EALDH1A1LMNAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3313825-A1 | GLUCOSE UPTAKE INHIBITORS | Kadmon Corporation, LLC (US) | 2018-05-02 | — | — | EP | disclosed |
| WO-2016210330-A1 | GLUCOSE UPTAKE INHIBITORS | KADMON CORPORATION, LLC (US) | 2016-12-29 | — | — | WO | disclosed |