Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29168977 | 1.00 | HSD17B10 (0.50) | HSD17B10KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL31460425 | 0.82 | MAPT (0.47) | KDM4EALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL26662208 | 0.82 | MAPT (0.47) | KDM4EALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL29985682 | 0.82 | MAOB (0.50) | HSD17B10KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL20535109 | 0.82 | MAOB (0.50) | HSD17B10KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL20535111 | 0.82 | MAOB (0.50) | HSD17B10KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL16012976 | 0.82 | LMNA (0.55) | ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL18343122 | 0.80 | HSD17B10 (0.50) | HSD17B10KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL28917337 | 0.79 | LMNA (0.40) | KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL28917335 | 0.79 | LMNA (0.40) | KDM4ELMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377665-A | PARP7 inhibitor and application thereof | 北京华森英诺生物科技有限公司 | 2024-01-09 | — | — | CN | disclosed |