Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SOD1 | P00441 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17138170 | 0.87 | GPBAR1 (0.60) | KDM4EGPBAR1LMNAFFAR1 | |
| SCHEMBL2209641 | 0.84 | MAOB (0.51) | MAOBKDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL4349792 | 0.84 | MAOB (0.55) | MAOBKDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL10154613 | 0.82 | ADRB2 (0.56) | GPBAR1LMNAKMT2AL3MBTL1 | |
| SCHEMBL12704205 | 0.82 | TSHR (0.43) | MAOBKDM4EHSD17B10ALDH1A1KMT2A | |
| SCHEMBL9698630 | 0.81 | NPSR1 (0.49) | KDM4EGPBAR1HSD17B10ALDH1A1LMNA | |
| SCHEMBL14027336 | 0.81 | ALDH1A1 (0.54) | MAOBKDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL19384259 | 0.81 | LMNA (0.61) | MAOBKDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL19384428 | 0.81 | LMNA (0.61) | MAOBKDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL9324039 | 0.81 | MAOB (0.51) | MAOBKDM4EHSD17B10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979331-A1 | TRISUBSTITUTED AMINE COMPOUNDS AS INHIBITORS OF -CHOLESTERYL ESTER TRANSFER PROTEIN CETP | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-10-15 | — | — | EP | disclosed |
| EP-1979341-A1 | TRISUBSTITUTED AMINE COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007088999-A1 | TRISUBSTITUTED AMINE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-08-09 | — | — | WO | disclosed |
| WO-2007088996-A1 | TRISUBSTITUTED AMINE COMPOUNDS AS INHIBITORS OF -CHOLESTERYL ESTER TRANSFER PROTEIN CETP | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-08-09 | — | — | WO | disclosed |