Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR known ✓ | P35968 | 1/20 | 0.41 |
| ▸ | PDGFRB known ✓ | P09619 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | DAO | P14920 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | DDO | Q99489 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980499 | 0.88 | AOC3 (0.54) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL30041175 | 0.88 | AOC3 (0.54) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL12003943 | 0.86 | AOC3 (0.52) | FLT3KDM4EMAPTDAOHPGD | |
| Methane SCHEMBL27716118 | 0.86 | AOC3 (0.52) | FLT3KDM4EMAPTDAOHPGD | |
| Phosphoric Acid SCHEMBL7651467 | 0.80 | RAB9A (0.59) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL29139308 | 0.80 | KDM4E (0.47) | FLT3KDM4EMAPTDAOHPGD | |
| Phosphoric Acid SCHEMBL27492635 | 0.77 | CYP19A1 (0.44) | FLT3DAONPC1MEN1KMT2A | |
| SCHEMBL29628104 | 0.74 | FLT3 (0.50) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL2993551 | 0.74 | FLT3 (0.50) | FLT3KDM4EMAPTDAOHPGD | |
| Phosphoric Acid SCHEMBL30909011 | 0.73 | KDM4E (0.56) | FLT3KDM4EMAPTDAOHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016209859-A1 | CHIMERIC POLYPEPTIDE, VACCINE AGAINST BABESIOSIS, IMMUNIZATION METHODS, DETECTION METHODS AND KIT | INSTITUTO NACIONAL DE TECNOLOGIA AGROPECUARIA (AR) | 2016-12-29 | — | — | WO | disclosed |
| CN-105021596-A | Concentration gradient based dry chemical test strip with multiple layers of films | ZENG RONGBIN | 2015-11-04 | — | — | CN | disclosed |
| CN-1256712-A | Plant Disease Control | NOVARTIS AG (CH) | 2000-06-14 | — | — | CN | disclosed |