Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.48 |
| ▸ | ICMT | O60725 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14950422 | 0.89 | BRD4 (0.43) | ALKICMTBRD4MCHR1ALDH1A1 | |
| SCHEMBL19151276 | 0.86 | BRD4 (0.41) | ALKICMTBRD4MCHR1ALDH1A1 | |
| SCHEMBL369219 | 0.86 | BRD4 (0.43) | ALKICMTBRD4MCHR1ALDH1A1 | |
| SCHEMBL17612728 | 0.86 | BRD4 (0.41) | ALKICMTUSP2MAPTBRD4 | |
| SCHEMBL10031971 | 0.82 | BRD4 (0.42) | BRD4ALDH1A1SCN9A | |
| SCHEMBL364465 | 0.81 | FDPS (0.60) | MAPTALDH1A1 | |
| SCHEMBL16769443 | 0.81 | LTA4H (0.45) | BRD4ALDH1A1SCN9A | |
| SCHEMBL10031677 | 0.80 | FDPS (0.46) | MAPTBRD4MCHR1ALDH1A1 | |
| SCHEMBL20852021 | 0.79 | BRD4 (0.42) | BRD4MCHR1ALDH1A1SCN9A | |
| SCHEMBL369666 | 0.77 | NPC1 (0.47) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3313823-A1 | METHOD FOR SYNTHESIZING MOLECULES HAVING A NITRILE OXIDE FUNCTION | Compagnie Générale des Etablissements Michelin (FR) | 2018-05-02 | — | — | EP | disclosed |
| WO-2016207263-A1 | METHOD FOR SYNTHESIZING MOLECULES HAVING A NITRILE OXIDE FUNCTION | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2016-12-29 | — | — | WO | disclosed |