Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | ICMT | O60725 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17612728 | 0.89 | BRD4 (0.41) | BRD4ALKSCN9AICMTPDK2 | |
| SCHEMBL19151276 | 0.89 | BRD4 (0.41) | BRD4ALKSCN9AICMTPDK2 | |
| SCHEMBL18344265 | 0.86 | ALK (0.48) | BRD4ALKSCN9AICMTMCHR1 | |
| SCHEMBL14950422 | 0.85 | BRD4 (0.43) | BRD4ALKSCN9AICMTPDK2 | |
| SCHEMBL10031971 | 0.78 | BRD4 (0.42) | BRD4SCN9APDK2SCN5ALTA4H | |
| SCHEMBL20852021 | 0.78 | BRD4 (0.42) | BRD4SCN9APDK2SCN5AMCHR1 | |
| SCHEMBL364465 | 0.77 | FDPS (0.60) | KDM4EALDH1A1 | |
| SCHEMBL16769443 | 0.77 | LTA4H (0.45) | BRD4SCN9APDK2LTA4HKDM4E | |
| SCHEMBL29442025 | 0.77 | SCN9A (0.42) | BRD4SCN9APDK2SCN5ASCN2A | |
| SCHEMBL366499 | 0.77 | SCN9A (0.42) | BRD4SCN9APDK2SCN5ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3313823-B1 | METHOD FOR SYNTHESIZING MOLECULES HAVING A NITRILE OXIDE FUNCTION | MICHELIN & CIE (FR) | 2022-11-09 | — | — | EP | disclosed |
| EP-3380340-B1 | RUBBER COMPOSITION | MICHELIN & CIE (FR) | 2021-03-17 | — | — | EP | disclosed |
| EP-3172242-B1 | POLYMER MODIFIED ALONG THE CHAIN AND PROCESS FOR THE SYNTHESIS THEREOF | MICHELIN & CIE (FR) | 2019-03-27 | — | — | EP | disclosed |
| WO-2018115747-A1 | TYRE FOR A VEHICLE CARRYING HEAVY LOADS, COMPRISING A NEW TREAD | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2018-06-28 | — | — | WO | disclosed |
| EP-2593437-B1 | MOLECULES HAVING COMBINABLE GROUPS | ARKEMA FRANCE (FR) | 2017-09-06 | — | — | EP | disclosed |
| EP-2593437-B1 | MOLECULES HAVING COMBINABLE GROUPS | ARKEMA FRANCE (FR) | 2017-09-06 | — | — | EP | disclosed |
| US-20170174794-A1 | POLYMER MODIFIED ALONG THE CHAIN AND PROCESS FOR THE SYNTHESIS THEREOF | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2017-06-22 | — | — | US | disclosed |
| US-20170158782-A1 | RUBBER COMPOSITION | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2017-06-08 | — | — | US | disclosed |
| WO-2017089706-A1 | RUBBER COMPOSITION | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2017-06-01 | — | — | WO | disclosed |
| WO-2017089708-A1 | RUBBER COMPOSITION | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2017-06-01 | — | — | WO | disclosed |
| US-20130197237-A1 | MOLECULES HAVING COMBINABLE GROUPS | ARKEMA FRANCE (FR) | 2013-08-01 | — | — | US | disclosed |
| US-20130131279-A1 | GRAFT POLYMER TO WHICH COMBINED NITROGEN MOLECULES ARE GRAFTED | Mchelin Recherche et Technique S.A. (CH) | 2013-05-23 | — | — | US | disclosed |
| US-20130131279-A1 | GRAFT POLYMER TO WHICH COMBINED NITROGEN MOLECULES ARE GRAFTED | Mchelin Recherche et Technique S.A. (CH) | 2013-05-23 | — | — | US | disclosed |
| EP-2593485-A1 | GRAFT POLYMER TO WHICH COMBINED NITROGEN MOLECULES ARE GRAFTED | Compagnie Générale des Etablissements Michelin (FR) | 2013-05-22 | — | — | EP | disclosed |
| EP-2593437-A1 | MOLECULES HAVING COMBINABLE GROUPS | Arkema France (FR) | 2013-05-22 | — | — | EP | disclosed |
| US-20130123418-A1 | RUBBER COMPOSITION CONTAINING A MODIFED ELASTOMER, METHOD FOR PREPARING SAME, AND TIRE CONTAINING SAME | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2013-05-16 | — | — | US | disclosed |
| WO-2012007441-A1 | GRAFT POLYMER TO WHICH COMBINED NITROGEN MOLECULES ARE GRAFTED | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007441-A1 | GRAFT POLYMER TO WHICH COMBINED NITROGEN MOLECULES ARE GRAFTED | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007684-A1 | MOLECULES HAVING COMBINABLE GROUPS | ARKEMA FRANCE (FR) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007684-A1 | MOLECULES HAVING COMBINABLE GROUPS | ARKEMA FRANCE (FR) | 2012-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197237-A1 | MOLECULES HAVING COMBINABLE GROUPS | NCAPH, NCL, PARG | BRD4 103/4885ALK 3179/4885SCN9A 4260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.