Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | CCKAR | P32238 | 1/20 | 0.30 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412162 | 0.91 | PTGDR2 (0.32) | PTGDR2DCTPP1 | |
| SCHEMBL1832617 | 0.89 | PTGDR2 (0.31) | PTGDR2 | |
| SCHEMBL1830821 | 0.89 | GPBAR1 (0.30) | PTGDR2 | |
| SCHEMBL2414690 | 0.88 | HTR6 (0.32) | PTGDR2CCKAR | |
| SCHEMBL2410517 | 0.88 | DHODH (0.31) | PTGDR2DHODH | |
| SCHEMBL2410668 | 0.88 | PTGDR2 (0.32) | PTGDR2 | |
| SCHEMBL2414830 | 0.88 | PTGDR2 (0.34) | PTGDR2 | |
| SCHEMBL1833794 | 0.88 | PTGDR2 (0.34) | PTGDR2CCKAR | |
| SCHEMBL2409445 | 0.88 | ESR1 (0.39) | PTGDR2CCKAR | |
| SCHEMBL2411402 | 0.87 | DHODH (0.30) | PTGDR2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172275-A1 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-07-14 | — | — | US | disclosed |
| EP-2318390-A1 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010024451-A1 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172275-A1 | PYRROLE COMPOUNDS | PRLHR, C1R, C1S | PTGDR2 387/4885DHODH 1109/4885CCKAR 372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.