Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4422687 | 0.95 | PTGDR2 (0.31) | PTGDR2RORCKDM2BCFTR | |
| SCHEMBL2410285 | 0.90 | PTGDR2 (0.33) | PTGDR2 | |
| SCHEMBL2409056 | 0.88 | KDM2B (0.35) | PTGDR2RORCKDM2BCFTRHSD11B1 | |
| SCHEMBL1834429 | 0.88 | PTGDR2 (0.32) | PTGDR2 | |
| SCHEMBL2412162 | 0.86 | PTGDR2 (0.32) | PTGDR2 | |
| SCHEMBL2410517 | 0.85 | DHODH (0.31) | PTGDR2 | |
| SCHEMBL2411094 | 0.85 | PTGDR2 (0.30) | PTGDR2 | |
| SCHEMBL2410118 | 0.85 | PPME1 (0.35) | PTGDR2RORCNR1H3SLC40A1 | |
| SCHEMBL2410603 | 0.84 | HTR6 (0.33) | PTGDR2CTSK | |
| SCHEMBL2414690 | 0.84 | HTR6 (0.32) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |