Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17188766 | 0.75 | KMT2A (0.57) | SMN1; SMN2RXFP1PTGS2ALDH1A1KMT2A | |
| SCHEMBL2238597 | 0.75 | ALDH1A1 (0.60) | GAASMN1; SMN2ALDH1A1RAB9AKMT2A | |
| SCHEMBL18962617 | 0.73 | MCOLN3 (0.55) | GAASMN1; SMN2TSHRALDH1A1RAB9A | |
| SCHEMBL18962622 | 0.73 | MCOLN3 (0.55) | GAASMN1; SMN2TSHRALDH1A1RAB9A | |
| SCHEMBL10673104 | 0.73 | ALDH1A1 (0.54) | SMN1; SMN2TSHRPTGS2ALDH1A1RAB9A | |
| SCHEMBL16264094 | 0.72 | MCOLN3 (0.54) | SMN1; SMN2TSHRALDH1A1RAB9AKMT2A | |
| SCHEMBL29944466 | 0.72 | ALDH1A1 (0.76) | GAASMN1; SMN2TSHRALDH1A1KMT2A | |
| SCHEMBL20953767 | 0.72 | KDM4E (0.50) | GAAALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL6841567 | 0.72 | KMT2A (0.57) | GAASMN1; SMN2ALDH1A1RAB9AKMT2A | |
| SCHEMBL12031645 | 0.71 | TSHR (0.62) | GAASMN1; SMN2TSHRALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9526786-B2 | Thermostabilization of proteins | THE TRUSTEE OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-12-27 | — | — | US | disclosed |