Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.57 |
| ▸ | MEN1 | O00255 | 10/20 | 0.57 |
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17188723 | 0.82 | GAA (0.49) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL18346800 | 0.75 | GAA (0.59) | KMT2AMEN1MAPTSMN1; SMN2PTGS2 | |
| SCHEMBL11137198 | 0.74 | KMT2A (0.70) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL12297590 | 0.74 | TLR9 (0.52) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL17188722 | 0.73 | CCNT1 (0.51) | KMT2AMEN1NPC1 | |
| SCHEMBL12297981 | 0.72 | MAPT (0.69) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL3179153 | 0.72 | KMT2A (0.52) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL12297565 | 0.72 | KMT2A (0.66) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL7988045 | 0.72 | RAB9A (0.62) | KMT2AMEN1MAPTNPC1MAPK1 | |
| SCHEMBL17188733 | 0.71 | GAA (0.40) | MAPTSMN1; SMN2NPC1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265606-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-10-21 | — | — | EP | disclosed |