SCHEMBL18348554

SCHEMBL18348554

N#Cc1ccc(-n2c3ccccc3c3cccc(-c4cccc5c6ccccc6n(-c6ccccc6-c6ccccc6C#N)c45)c32)cc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
USP14 P54578 2/20 0.35
DUSP3 P51452 1/20 0.35
IDO1 P14902 1/20 0.35
TDO2 P48775 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
RPS6KB1 P23443 1/20 0.34
GSK3B P49841 1/20 0.34
NR3C1 P04150 1/20 0.34
TDP2 O95551 2/20 0.33
SLC22A12 Q96S37 1/20 0.33
BRD4 O60885 1/20 0.33
PGR P06401 1/20 0.33
PTGER4 P35408 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HIF1A Q16665 1/20 0.33
CNR1 P21554 1/20 0.32
IMPDH2 P12268 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21202489 0.93 USP14 (0.36) USP14DUSP3IDO1TDO2KDM4E
SCHEMBL18347417 0.92 DUSP3 (0.38) USP14DUSP3IDO1TDO2KDM4E
SCHEMBL18348374 0.91 USP14 (0.36) USP14DUSP3IDO1TDO2KDM4E
SCHEMBL18348424 0.91 USP14 (0.36) USP14DUSP3IDO1TDO2KDM4E
SCHEMBL18347447 0.91 DUSP3 (0.37) USP14DUSP3IDO1TDO2KDM4E
SCHEMBL18348537 0.91 ATM (0.44) DUSP3KDM4EATML3MBTL1NR3C1
SCHEMBL18348551 0.89 ESR2 (0.42) USP14DUSP3IDO1TDO2KDM4E
SCHEMBL21202423 0.87 PTGER4 (0.36) USP14DUSP3IDO1TDO2NR3C1
SCHEMBL21202493 0.87 PTGER4 (0.36) USP14DUSP3IDO1TDO2NR3C1
SCHEMBL18347416 0.87 PTGER4 (0.37) USP14DUSP3IDO1TDO2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10367151-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-07-30 US disclosed
US-20160380209-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160380209-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 USP14 3751/4885DUSP3 4833/4885IDO1 2528/4885
US-10367151-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 USP14 3751/4885DUSP3 4833/4885IDO1 2528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.