Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 7/20 | 0.40 |
| ▸ | CA12 | O43570 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.38 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25346209 | 0.91 | THRB (0.46) | THRBCYP2D6HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL16392960 | 0.91 | THRB (0.46) | THRBCYP2D6HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL5973361 | 0.91 | THRB (0.46) | THRBCYP2D6HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL18349751 | 0.88 | THRB (0.40) | THRBCYP2D6HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL5973544 | 0.85 | THRB (0.45) | THRBCYP2D6HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL18349750 | 0.85 | LMNA (0.38) | THRBCYP2D6HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL25976391 | 0.82 | DUSP3 (0.32) | — | |
| SCHEMBL1971892 | 0.82 | THRB (0.40) | THRBCYP2D6HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL16392969 | 0.81 | TSHR (0.42) | THRBCYP2D6HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL16392956 | 0.78 | TSHR (0.39) | THRBCYP2D6HSD17B10LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160376585-A1 | OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION | BANK OF AMERICA, N.A. | 2016-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160376585-A1 | OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION | IGF2R, IRS1, INSR | THRB 848/4885CYP2D6 4469/4885HSD17B10 3782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.