Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28677927 | 0.67 | PDE4B (0.49) | PDE4B | |
| SCHEMBL31732376 | 0.65 | PDE4B (0.41) | PDE4B | |
| SCHEMBL26795366 | 0.65 | PDE4B (0.41) | PDE4B | |
| SCHEMBL31145931 | 0.62 | PDE4B (0.41) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL29965443 | 0.61 | PDE4B (0.40) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL26660637 | 0.61 | MAP4K1 (0.45) | — | |
| SCHEMBL31501830 | 0.61 | MAP4K1 (0.45) | — | |
| SCHEMBL31501903 | 0.61 | POLB (0.43) | — | |
| SCHEMBL5133297 | 0.60 | PDE4B (0.49) | PDE4B | |
| SCHEMBL19930075 | 0.58 | YTHDC1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9533986-B2 | Bicyclic dihydropyridone kinase inhibitors | PORTOLA PHARMACEUTICALS, INC. (US) | 2017-01-03 | — | — | US | disclosed |