Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17831026 | 1.00 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1KDM4ELMNARECQL | |
| SCHEMBL15032082 | 0.86 | SMN1; SMN2 (0.72) | SMN1; SMN2ALDH1A1KDM4ELMNARECQL | |
| SCHEMBL23992348 | 0.84 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1KDM4ELMNARECQL | |
| SCHEMBL13025225 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1KDM4ELMNARECQL | |
| SCHEMBL12705075 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1KDM4ELMNARECQL | |
| SCHEMBL670003 | 0.81 | PLA2G7 (0.54) | SMN1; SMN2ALDH1A1KDM4ELMNARECQL | |
| SCHEMBL670004 | 0.81 | PLA2G7 (0.54) | SMN1; SMN2ALDH1A1KDM4ELMNARECQL | |
| SCHEMBL14077931 | 0.80 | PLA2G7 (0.53) | SMN1; SMN2ALDH1A1KDM4ELMNARECQL | |
| SCHEMBL19303336 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1KDM4ELMNARECQL | |
| SCHEMBL19296378 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1KDM4ELMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11311636-B2 | Radiotracer compositions and methods | GE HEALTHCARE LIMITED (GB) | 2022-04-26 | — | — | US | disclosed |
| US-20190275182-A1 | RADIOTRACER COMPOSITIONS AND METHODS | GE HEALTHCARE LIMITED (GB) | 2019-09-12 | — | — | US | disclosed |
| US-10300156-B2 | Radiotracer compositions and methods | GE HEALTHCARE LIMITED (GB) | 2019-05-28 | — | — | US | disclosed |
| US-9533059-B2 | Peptide radiotracer compositions | GE HEALTHCARE LIMITED (GB) | 2017-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190275182-A1 | RADIOTRACER COMPOSITIONS AND METHODS | MET, METTL14, MEN1 | SMN1; SMN2 3898/4885ALDH1A1 4112/4885KDM4E 2261/4885 |
| US-10300156-B2 | Radiotracer compositions and methods | MET, METTL14, MEN1 | SMN1; SMN2 3898/4885ALDH1A1 4112/4885KDM4E 2261/4885 |
| US-11311636-B2 | Radiotracer compositions and methods | MET, METTL14, MEN1 | SMN1; SMN2 3898/4885ALDH1A1 4112/4885KDM4E 2261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.