Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 17/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1831956 | 0.78 | NPC1 (0.57) | NPC1RAB9AHDAC4HDAC6HDAC1 | |
| SCHEMBL30935725 | 0.77 | NPC1 (0.52) | NPC1RAB9AMAPT | |
| SCHEMBL6490110 | 0.77 | RAB9A (0.70) | NPC1RAB9AMAPT | |
| SCHEMBL2888002 | 0.77 | HDAC4 (0.50) | HDAC4HDAC6HDAC1HDAC8 | |
| SCHEMBL19042602 | 0.77 | HDAC4 (0.53) | HDAC4HDAC6HDAC8 | |
| SCHEMBL1836408 | 0.77 | NPC1 (0.40) | NPC1RAB9AHDAC4HDAC6HDAC1 | |
| SCHEMBL2226996 | 0.76 | NPC1 (0.62) | NPC1RAB9AHDAC4HDAC6HDAC1 | |
| SCHEMBL1831038 | 0.75 | MAPT (0.48) | NPC1RAB9AMAPT | |
| SCHEMBL20528695 | 0.75 | HDAC4 (0.57) | HDAC4HDAC6HDAC1HDAC8 | |
| SCHEMBL31304852 | 0.75 | MAPT (0.52) | NPC1RAB9AHDAC4HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180343864-A1 | Substituted Oxadiazoles for Combating Phytopathogenic Fungi | BASF SE (DE) | 2018-12-06 | — | — | US | disclosed |
| EP-3373735-A1 | SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI | BASF SE (DE) | 2018-09-19 | — | — | EP | disclosed |
| WO-2017081309-A1 | SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI | BASF SE (DE) | 2017-05-18 | — | — | WO | disclosed |
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
| EP-2318374-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | Bayer CropScience AG (DE) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010012442-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AG (DE) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180343864-A1 | Substituted Oxadiazoles for Combating Phytopathogenic Fungi | CYP51A1, OSR1, FOXO3 | NPC1 3455/4885RAB9A 4593/4885HDAC4 2557/4885 |
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | DDT, BRD9, BCL2A1 | NPC1 2992/4885RAB9A 405/4885HDAC4 620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.