Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.70 |
| ▸ | NPC1 | O15118 | 8/20 | 0.70 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1835286 | 0.77 | NPC1 (0.59) | RAB9ANPC1MAPT | |
| SCHEMBL6495701 | 0.77 | NR1H4 (0.63) | RAB9ANPC1MAPTSMN1; SMN2NR1H4 | |
| SCHEMBL14740084 | 0.76 | RAB9A (0.56) | RAB9ANPC1MAPTSMN1; SMN2HPGD | |
| SCHEMBL27467205 | 0.74 | NR1H4 (0.63) | RAB9ANPC1MAPTSMN1; SMN2NR1H4 | |
| SCHEMBL2249542 | 0.72 | SMN1; SMN2 (0.60) | RAB9ANPC1MAPTSMN1; SMN2HPGD | |
| SCHEMBL6267898 | 0.72 | MAPT (0.63) | RAB9ANPC1MAPTSMN1; SMN2HPGD | |
| SCHEMBL29923752 | 0.72 | TSHR (0.64) | RAB9AMAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL359844 | 0.72 | TSHR (0.64) | RAB9AMAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL11293963 | 0.72 | MAPT (0.60) | RAB9ANPC1MAPTSMN1; SMN2HPGD | |
| SCHEMBL5569675 | 0.71 | MAPT (0.57) | RAB9ANPC1MAPTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6893650-B1 | N2-phenylamidine derivatives | BAYER CROPSCIENCE GMBH (DE) | 2005-05-17 | — | — | US | disclosed |
| EP-1150944-B1 | N2-PHENYLAMIDINE DERIVATIVES | BAYER CROPSCIENCE GMBH (DE) | 2003-08-20 | — | — | EP | disclosed |
| EP-1150944-A1 | N2-PHENYLAMIDINE DERIVATIVES | Aventis CropScience GmbH (DE) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000046184-A1 | N2-PHENYLAMIDINE DERIVATIVES | AVENTIS CROPSCIENCE GMBH (FR) | 2000-08-10 | — | — | WO | disclosed |